NCCN: Continuing Education
NCCN: Continuing Education
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DOI：
10.6004/jnccn.2020.0017
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发表时间：
2020-04-01
影响因子：
13.4
通讯作者：
Darlow, Susan D.
中科院分区：
文献类型：
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作者：
Daly, Mary B.;Pilarski, Robert;Darlow, Susan D.
NCCN 遗传/家族高风险评估指南：乳腺癌、卵巢癌和胰腺癌为遗传性癌症综合征的基因检测和咨询提供建议，并为被诊断患有与这些癌症风险增加相关的综合征的患者提供风险管理建议。 NCCN 小组至少每年召开一次会议，审查意见、检查相关新数据并重新评估和更新建议。这些 NCCN 指南见解总结了专家组的讨论和最新建议，涉及与 BRCA1/2 以外的乳腺癌和卵巢癌相关的高外显率基因标准、胰腺筛查和与胰腺癌相关的基因、用于系统治疗决策目的的基因检测以及对德系犹太血统人群的检测。
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic provide recommendations for genetic testing and counseling for hereditary cancer syndromes, and risk management recommendations for patients who are diagnosed with syndromes associated with an increased risk of these cancers. The NCCN panel meets at least annually to review comments, examine relevant new data, and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel's discussion and most recent recommendations regarding criteria for high-penetrance genes associated with breast and ovarian cancer beyond BRCA1/2, pancreas screening and genes associated with pancreatic cancer, genetic testing for the purpose of systemic therapy decision-making, and testing for people with Ashkenazi Jewish ancestry.