Retrievable puncture anchor traction method for EUS-guided gallbladder drainage: a porcine study

Retrievable puncture anchor traction method for EUS-guided gallbladder drainage: a porcine study
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EUS引导下胆囊引流的可回收穿刺锚牵引法:猪研究

DOI:
10.1016/j.gie.2018.07.019
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发表时间:
2018-12-01
影响因子:
7.7
通讯作者:
Wang, Guoxin
Wang, Guoxin
中科院分区:
医学1区
文献类型:
--
作者:
Zhang, Kai;Sun, Siyu;Wang, Guoxin

文献摘要

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背景和目的:EUS引导胆囊引流(EUS-GBD)对内镜医师来说是一项具有挑战性的技术,需要高水平的技能。EUS-GBD具有挑战性,因为胆囊很容易塌陷。为了解决这一问题,我们旨在开发一种用于EUS-GBD的可回收穿刺锚牵引(RPAT)方法。我们评估和比较了成功率,安全性和结果的RPAT方法EUS-GBD与EUS-GBD没有RPAT使用猪model.Methods:在总数为16巴马小型猪(体重15-20公斤)随机分为实验组(n = 8)和对照组(n = 8)。实验组采用RPAT法,对照组采用不带可回收穿刺锚的EUS-GBD法。结果:实验组8只动物均成功完成EUS-GBD手术(100%),实验组8只动物均成功完成EUS-GBD手术(100%),实验组8只动物均成功完成EUS-GBD手术(100%)。而对照组中仅4头(50%)成功进行EUS-GBD,其余4头因胆囊塌陷导致EUS-GBD失败而死亡。结论:RPAT有助于提高EUS-GBD的成功率,减少胆囊塌陷。因此,我们相信这种方法可以在不久的将来应用于EUS-GBD。此外,RPAT将提高EUS-GBD的安全性。
Background and Aims: EUS-guided gallbladder drainage (EUS-GBD) is a challenging technique for endoscopists that requires a high level of skill. EUS-GBD is challenging because the gallbladder can be easily collapsed. To resolve this issue, we aimed to develop a retrievable puncture anchor traction (RPAT) method for EUS-GBD. We evaluated and compared the success rate, safety, and outcomes of the RPAT method for EUS-GBD against EUS-GBD without RPAT using a porcine model.Methods: In total, 16 Bama mini pigs (weighing 15-20 kg) were randomly divided into an experimental group (n = 8) and a control group (n = 8). The RPAT method was performed in the experimental group and EUS-GBD without retrievable puncture anchor was performed in the control group. Incidence of operative adverse events, wound healing, and success rates of EUS-GBD were compared and analyzed between the experimental group and the control group.Results: All EUS-GBD procedures were successfully performed in all 8 animals in the experimental group (100%). However, in the control group, EUS-GBD was successfully performed only on 4 pigs (50%); the remaining 4 pigs died because of EUS-GBD failure caused by gallbladder collapse leading to unsuccessful frontal stent release.Conclusions: RPAT helped increase the success rate of EUS-GBD and could reduce gallbladder collapse. Therefore, we believe this method can be applied to EUS-GBD in the near future. Furthermore, RPAT will enhance the safety of EUS-GBD.