Targeting and retention of magnetic targeted carriers (MTCs) enhancing intra-arterial chemotherapy
Targeting and retention of magnetic targeted carriers (MTCs) enhancing intra-arterial chemotherapy
复制标题
DOI：
10.1016/s0304-8853(98)00584-8
复制
发表时间：
1999-04-01
影响因子：
2.7
通讯作者：
Bittner, C
中科院分区：
文献类型：
--
作者：
Goodwin, S;Peterson, C;Bittner, C
在猪模型中，在动脉内输注后，将MTCs磁靶向并保留在感兴趣的区域。去除磁场后，MTCs没有重新分布。组织病理学结果显示磁场区域内颗粒密度较高。间质中可见颗粒，偶尔在动脉内可见颗粒。化疗药物的区域输送将使用这项技术进行测试。(C)1999 Elsevier Science B.V.保留所有权利。
MTCs were magnetically targeted and retained at a region of interest in a swine model after intra-arterial infusion. MTCs did not redistribute after removal of the magnetic field. Histopathology results demonstrated high particle density in the area of the magnetic field. Particles were observed in the interstitium and occasionally intra-arterially. Regional delivery of chemotherapeutic drugs will be tested with this technology. (C) 1999 Elsevier Science B.V. All rights reserved.