Role of azoles in antifungal therapy.

Role of azoles in antifungal therapy.
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唑类在抗真菌治疗中的作用。

DOI:
10.1093/clinids/22.supplement_2.s148
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发表时间:
1996
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Kauffman,CA
Kauffman,CA
中科院分区:
--
文献类型:
--
作者:
Kauffman,CA

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在抗真菌药物中加入伊曲康唑和氟康唑,对于地方性和机会性真菌病来说,毒性较小,易于管理。伊曲康唑已成为大多数轻至中度组织胞浆菌病、芽生菌病和孢子丝菌病患者的首选治疗方法。伊曲康唑或氟康唑均可有效治疗球孢子菌病;氟康唑已成为治疗球虫性脑膜炎的首选药物。在几个大型合作试验中,氟康唑已被证明在治疗念珠菌血症、局部形式的粘膜皮肤和内脏念珠菌病以及隐球菌性脑膜炎方面具有有用的作用。
The addition of itraconazole and fluconazole to the antifungal armamentarium has resulted in less toxic, easily administered therapy for both endemic and opportunistic mycoses. Itraconazole has become the treatment of choice for most patients with mild-to-moderate histoplasmosis, blastomycosis, and sporotrichosis. Coccidioidomycosis is effectively treated with either itraconazole or fluconazole; fluconazole has become the drug of choice for the treatment of coccidioidal meningitis. In several large cooperative trials, fluconazole has been shown to have a useful role in the treatment of patients with candidemia, localized forms of mucocutaneous and visceral candidiasis, and cryptococcal meningitis.
伊曲康唑对中性粒细胞减少症患者全身真菌感染的疗效:与两性霉素 B 的随机比较研究。
DOI: --
发表时间: 1991
影响因子: 28.2
作者:
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DOI: --
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影响因子: --
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影响因子: --
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DOI: 10.1111/j.1439-0507.1992.tb00836.x
发表时间: 1992-05-01
期刊: MYCOSES
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作者:
DIAZ, IAC;CIVILA, E;ALZUETA, G
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