BIOINFORMATICS APPLICATIONS
BIOINFORMATICS APPLICATIONS
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通讯作者:
R. She;J. S. Chu;B. Uyar;Jun Wang;Ke Wang;Nansheng Chen
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作者:
R. She;J. S. Chu;B. Uyar;Jun Wang;Ke Wang;Nansheng Chen
Motivation: BLAST users frequently expect to obtain homologous genes with certain similarity to their query genes. But what they get from BLAST searches are often collections of local alignments called high-scoring segment pairs (HSPs). On the other hand, most homology-based gene finders have been built using computation-intensive algorithms, without taking full advantage of BLAST searches that have been perfected over the last decades. Results: Here we report an efficient algorithm, genBlastG that directly uses the HSPs reported by BLAST to define high-quality gene models.