G-InforBIO: integrated system for microbial genomics
G-InforBIO: integrated system for microbial genomics
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DOI：
10.1186/1471-2105-7-368
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发表时间：
2006-08-04
影响因子：
3
通讯作者：
Sugawara, Hideaki
中科院分区：
文献类型：
--
作者：
Tanaka, Naoto;Abe, Takashi;Sugawara, Hideaki
背景：基因组数据库包含各种各样的信息，包括基因注释、核苷酸和氨基酸序列。整合这些信息用于基因组研究并不容易。有几个工具，基因组数据的综合分析，因此，我们开发的软件，使用户能够处理，操作和分析基因组数据与各种序列analysisprogrammes.Results：G-InforBIO系统是一种新的工具，基因组数据管理和序列分析。该系统可以将编码为可扩展标记语言文档的基因组数据作为格式化文本文档导入，包括来自日本DNA数据库和编码为平面文件的GenBank的注释和序列。基因组数据库在导入后自动构建，数据库可以导出为可扩展标记语言格式的文档或制表符分隔的文本。用户可以通过关键字检索从数据库中检索数据，编辑基因注释数据，并使用G-InforBIO处理数据。此外，在G-InforBIO数据库中的信息可以无缝地分析与9个不同的软件程序，包括程序聚类和同源性analysis.Conclusion：G-InforBIO系统简化了基因组分析，通过整合几个可用的软件程序，允许有效地处理和操纵基因组数据。G-InforBIO可从下载网站免费获得。
Background: Genome databases contain diverse kinds of information, including gene annotations and nucleotide and amino acid sequences. It is not easy to integrate such information for genomic study. There are few tools for integrated analyses of genomic data, therefore, we developed software that enables users to handle, manipulate, and analyze genome data with a variety of sequence analysis programs.Results: The G-InforBIO system is a novel tool for genome data management and sequence analysis. The system can import genome data encoded as eXtensible Markup Language documents as formatted text documents, including annotations and sequences, from DNA Data Bank of Japan and GenBank encoded as flat files. The genome database is constructed automatically after importing, and the database can be exported as documents formatted with eXtensible Markup Language or tab-deliminated text. Users can retrieve data from the database by keyword searches, edit annotation data of genes, and process data with G-InforBIO. In addition, information in the G-InforBIO database can be analyzed seamlessly with nine different software programs, including programs for clustering and homology analyses.Conclusion: The G-InforBIO system simplifies genome analyses by integrating several available software programs to allow efficient handling and manipulation of genome data. G-InforBIO is freely available from the download site.