Ultrasonographic evaluation of invasive lobular carcinoma
Ultrasonographic evaluation of invasive lobular carcinoma
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DOI：
10.3109/02841859909177749
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发表时间：
1999-07-01
期刊：
影响因子：
1.3
通讯作者：
Skjorten, F
中科院分区：
文献类型：
--
作者：
Skaane, P;Skjorten, F
目的.比较浸润性小叶癌（ILC）的超声（US）和钼靶X线表现及肿瘤大小测量。比较95例单纯ILC患者的超声诊断和钼靶X线表现，其中46例可触及，49例不可触及。对95例乳腺癌患者中的70例患者的钼靶X线、超声和病理检查结果进行散点图和相关性分析。超声诊断恶性肿瘤82例（86.3%），局灶性异常5例（5.3%），正常2例。最常见的钼靶X线表现为毛刺状肿块（57%）和局灶性不对称密度（15%）。在12例乳腺X线检查结果正常或可疑的患者中，US正确诊断了8例。影像学和病理学对肿瘤大小评估的相关性显示，包括“晕圈”在内的US测量（r=0.69）上级乳腺X线摄影（r=0.59）。两种方法都严重低估了大于30 mm的ILC。ILC的超声诊断多为恶性肿瘤。包括“晕圈”的US肿瘤测量最准确地预测肿瘤大小。ILC的影像学测量值与组织学上肿瘤直径之间的相关性低于混合癌人群。
Purpose. To compare ultrasonographic (US) and mammographic findings and tumor size measurements of invasive lobular carcinoma (ILC).Material and Methods. US diagnoses and mammographic findings were compared in 95 patients with pure ILC, including 46 palpable and 49 nonpalpable tumors. The diameters of tumors measured by mammography, US, and pathology were compared in 70 of the 95 patients using scatter plots and correlation analysis.Results. Eighty-two (86.3%) of the ILCs were correctly diagnosed as malignant tumor, 5 (5.3%) were diagnosed as focal abnormality and only 2 patients had normal findings on US.; The most common mammographic findings were a spiculated mass (57%) and a focal asymmetric density (15%). US correctly diagnosed 8 of 12 patients with normal or equivocal mammographic findings. The correlation of tumor size assessment on imaging and pathology revealed that US measurements including the "halo" (r=0.69) was superior to that of mammography (r=0.59). ILCs larger than 30 mm were heavily underestimated by both methods.Conclusion. Malignant tumor was diagnosed on US in most of the patients with ILC. US tumor measurement including the "halo" predicted tumor size most accurately. The correlation between imaging measurements and tumor diameter on histology was lower for ILCs than reported for populations of mixed carcinomas.