1,3-dipolar cycloaddition reactions of benzo[b]thiophene 1,1-dioxide with azomethine ylides
1,3-dipolar cycloaddition reactions of benzo[b]thiophene 1,1-dioxide with azomethine ylides
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DOI：
10.1016/j.tetlet.2006.05.064
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发表时间：
2006-07-17
影响因子：
1.8
通讯作者：
Westwood, Robert
中科院分区：
文献类型：
--
作者：
Malatesti, Nela;Boa, Andrew N.;Westwood, Robert
通过1，3-偶极环加成反应合成了新的苯并[B]噻吩1，1-二氧化物吡咯衍生物。苯并[B]噻吩1，1-二氧化物与稳定化的甲亚胺叶立德反应，产率低，但立体选择性高，而与非稳定化的甲亚胺叶立德反应，总产率高，但立体选择性低。(c)2006爱思唯尔有限公司保留所有权利。
New pyrrolo derivatives of benzo[b]thiophene 1,1-dioxide have been synthesised via 1,3-dipolar cycloaddition reactions. Reaction of benzo[b]thiophene 1,1-dioxide with stabilised azomethine ylides gave products in low yield but high stereoselectivity whereas reaction with non-stabilised azomethine ylides gave high overall yields but low stereoselectivity. (c) 2006 Elsevier Ltd. All rights reserved.