The incidence of eating disorders in a Danish register study: Associations with suicide risk and mortality.
The incidence of eating disorders in a Danish register study: Associations with suicide risk and mortality.
复制标题
丹麦登记研究中饮食失调的发生率：与自杀风险和死亡率的关联。
DOI：
10.1016/j.jpsychires.2015.03.003
复制
发表时间：
2015
影响因子：
4.8
通讯作者：
Bulik,CynthiaM
中科院分区：
文献类型：
--
作者：
Zerwas,Stephanie;Larsen,JanneTidselbak;Petersen,Liselotte;Thornton,LauraM;Mortensen,PrebenBo;Bulik,CynthiaM
我们的目的是描述神经性厌食症（AN）、神经性贪食症（BN）和未另行说明的进食障碍（EDNOS）的发病率和累积发病率，并检查进食障碍诊断、自杀企图和死亡率之间的关联。纳入了1989年至2006年期间出生于丹麦的个体（N = 966，141，51.3%为男性）。进食障碍诊断（AN，广义AN，BN，EDNOS）来自丹麦精神病学中央研究登记处（PCRR）和丹麦国家患者登记处（NPR）。自杀企图和死亡记录在NPR、PCRR和丹麦民事登记系统（CRS）中。在女性中，AN在大约15岁时具有峰值危险，BN在22岁时，EDNOS具有跨越18岁至22岁的扩展峰值。与没有饮食失调的个体相比，饮食失调的诊断预测了死亡和自杀企图的显著更高风险。在男性中，诊断的峰值风险早于女性。目前的研究是对女性和男性饮食失调发病率、自杀企图和死亡的最大和最长的研究之一。饮食失调伴随着自杀企图和死亡的风险增加，即使在年轻人中也是如此。
Our aim was to characterize the incidence rates and cumulative incidence of anorexia nervosa (AN), bulimia nervosa (BN), and eating disorder not otherwise specified (EDNOS), and examine associations among eating disorder diagnoses, suicide attempts, and mortality. Individuals born in Denmark between 1989 and 2006 were included (N = 966,141, 51.3% male). Eating disorders diagnoses (AN, broad AN, BN, EDNOS) were drawn from the Danish Psychiatric Central Research Register (PCRR) and Danish National Patient Register (NPR). Suicide attempts and deaths were captured in the NPR, the PCRR, and the Danish Civil Registration System (CRS). In females, AN had a peak hazard at approximately age 15 years, BN at 22 years, and EDNOS had an extended peak that spanned 18 years–22 years. Eating disorder diagnoses predicted a significantly higher hazard for death and suicide attempt compared with the referent of individuals with no eating disorders. In males, peak hazard for diagnosis was earlier than in females. The present study represents one of the largest and longest studies of eating disorder incidence and suicide attempts and death in both females and males. Eating disorders are accompanied by increased hazard of suicide attempts and death even in young adults.