The prevalence of asthma and COPD in Italy: A practice-based study
The prevalence of asthma and COPD in Italy: A practice-based study
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DOI：
10.1016/j.rmed.2010.09.022
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发表时间：
2011-03-01
影响因子：
4.3
通讯作者：
Calzetta, Luigino
中科院分区：
文献类型：
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作者：
Cazzola, Mario;Puxeddu, Ermanno;Calzetta, Luigino
我们利用从意大利全科医生学院拥有的健康搜索数据库中获得的信息，在具有代表性的成人全国样本中进行了一项基于人群的哮喘和慢性阻塞性肺病横断面流行病学调查。截至2009年12月底，患者人数为909,638人(男性429,962人，女性479,676人；男女比例[男/女]：0.89)，年龄=14岁的全科医生被选为整个意大利人口的代表。根据ICD-9编码识别哮喘和COPD病例。总样本包括55500名哮喘患者(占总人口的6.10%；5.49%的男性和6.64%的女性；男女比例：0.74)和25762名患有慢性阻塞性肺疾病的患者(占总人口的2.83%；男性的3.51%和女性的2.23%；男性和女性的比例：1.41)。一般人群哮喘/COPD比值为2.16。之所以选择优势比(OR)，是因为哮喘和COPD的患病率低于10%。男性和女性发生哮喘的OR均随年龄增长而降低，但在第一年龄组(15-34岁)，男性高于女性(1.69比1.00)，但从35岁开始男性低于1，男性从75岁开始高于女性。相反，男性和女性发生COPD的OR值从55岁开始均大于1，并随着年龄的增长而逐渐增加(75~84岁组，男性为6.16，女性为4.07)。(C)2010爱思唯尔有限公司。保留所有权利。
We conducted a population-based cross-sectional epidemiologic survey of asthma and COPD in an adult representative national sample using information obtained from the Health Search Database owned by the Italian College of General Practitioners. General Practitioners who had a list of patient population of 909,638 individuals (429,962 men and 479,676 women; man/woman ratio [M/WR]: 0.89) >= 14 years old at the end of December 2009 were selected to be representatives of the whole Italian population. Cases of asthma and COPD were identified on the basis of the ICD-9 codes. The total sample included 55,500 (6.10% of the entire population; 5.49% of men and 6.64% of women; M/WR: 0.74) subjects suffering from asthma and 25,762 (2.83% of the entire population; 3.51% of men and 2.23% of women; M/WR: 1.41) subjects suffering from COPD. The asthma/COPD ratio in general population was 2.16. The odds ratio (OR) was chosen because asthma and COPD had a prevalence less than 10%. The OR of developing asthma decreased with age both in men and women, but in the first group of age (15-34 years) it was higher in men vs. women (1.69 vs. 1.00) although it became lower than 1 from 35 years old and up in men and from 75 years old and up in women. On the contrary, the OR of developing COPD became higher than 1 from 55 years old and up both in men and in women and progressively increased with age (in the group 75-84 years, it was 6.16 in men and 4.07 in women, respectively). (C) 2010 Elsevier Ltd. All rights reserved.