In vivo demonstration of noninvasive thermal surgery of the liver and kidney using an ultrasonic phased array
In vivo demonstration of noninvasive thermal surgery of the liver and kidney using an ultrasonic phased array
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DOI：
10.1016/s0301-5629(99)00053-8
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发表时间：
1999-09-01
影响因子：
2.9
通讯作者：
Hynynen, K
中科院分区：
文献类型：
--
作者：
Daum, DR;Smith, NB;Hynynen, K
A 256-element, continuous-wave ultrasonic phased array has been used to thermally coagulate deep-seated liver and kidney tissue. The array elements were formed on a 1-3 piezocomposite bowl with a 10-cm radius of curvature and 12-cm diameter. The 0.65 x 0.65 cm(2) projection elements were driven at 1.1 MHz by a custom-built amplifier system. A series of in vivo porcine experiments demonstrated the ability to coagulate liver and kidney tissue using the large-scale phased array. The temperature response of the treatment was guided and monitored using magnetic resonance (MR) images, Focal lesion volumes greater than 0.5 cm(3) in kidney and 2 cm(3) in liver were formed from a single 20-s sonication, (C) 1999 World Federation for Ultrasound in Medicine & Biology.
