Factors affecting the quality of life in patients with epilepsy in Seoul, South Korea
Factors affecting the quality of life in patients with epilepsy in Seoul, South Korea
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DOI：
10.1046/j.1600-0404.2003.00151.x
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发表时间：
2003-12-01
影响因子：
3.5
通讯作者：
Lee, S
中科院分区：
文献类型：
--
作者：
Choi-Kwon, S;Chung, C;Lee, S
▽目的=在社会对癫痫病人的偏见仍然很明显的韩国，癫痫病人的生活质量（QOL）的水平和影响因素可能有所不同。然而，这些问题尚未得到妥善解决。方法：我们对在首尔大学医院门诊就诊的154例癫痫患者进行了连续鉴定。两名研究护士使用标准化问卷进行访谈，其中包括有关癫痫发作特征、抑郁/焦虑症状、社会支持、家庭生活/社会生活满意度和日常生活活动（adl）的数据。采用《癫痫生活质量量表》（QOLIE-31）评价患者的生活质量。结果-影响生活质量的因素有：年龄（P < 0.01）、受教育年限（P < 0.01）、就业状况（P < 0.05）、就业类型（P < 0.05）、经济状况（P < 0.05）、癫痫发作频率（P < 0.01）、抗癫痫药物用量（P < 0.01）、家庭生活/社会生活不满（P < 0.01）、社会支持（P < 0.01）、焦虑、抑郁症状（P < 0.01）、ADL功能障碍（P < 0.01）。多元回归分析发现，焦虑症状是影响癫痫患者生活质量下降的最重要因素，抑郁（P < 0.01）、社会生活不满（P < 0.01）、ADL功能障碍（P < 0.05）、发作频率（P < 0.05）也是影响癫痫患者生活质量下降的重要因素。结论：心理社会因素对韩国癫痫患者生活质量的影响大于生理因素。认识到这些因素将引导卫生专业人员制定不同的策略来改善这些患者的生活质量。
Objectives - The level of, and factors affecting the quality of life (QOL) in patients with epilepsy may be different in Korea where social prejudice toward them is still pronounced. However, these issues have not yet been addressed properly. Methods - We consecutively identified 154 epilepsy patients who visited the outpatient clinic at the Seoul National University Hospital. An interview was performed by two research nurses with the use of a standardized questionnaire, which included data pertaining to seizure characteristics, symptoms of depression/anxiety, social support, family life/social life satisfaction, and the activities of daily living (ADLs). The QOL was assessed with the use of QOL in Epilepsy Inventory (QOLIE-31). Results - Factors affecting the QOL were: age (P < 0.01), education in years (P < 0.01), employment status (P < 0.05), employment type (P < 0.05), current economic status (P < 0.05), seizure frequency (P < 0.01), the number of antiepileptic drugs (P < 0.01), family life/social life dissatisfaction (P < 0.01, respectively), social support (P < 0.01), the symptoms of anxiety and depression (P < 0.01, respectively) and ADL dysfunction (P < 0.01). In multiple regression analysis, the symptom of anxiety was the most important factor in explaining lower QOL in patients with epilepsy, while depression (P < 0.01), social life dissatisfaction (P < 0.01), ADL dysfunction (P < 0.05) and seizure frequency (P < 0.05) were also significant factors. Conclusions - Psycho-social factors outweighed the physical factors in determining QOL in Korean epilepsy patients. Recognition of these factors will lead health professionals to develop different strategies to improve the QOL of these patients.