Effectiveness of a physical activity program on cardiovascular disease risk in adult primary health-care users: the "Pas-a-Pas" community intervention trial.
Effectiveness of a physical activity program on cardiovascular disease risk in adult primary health-care users: the "Pas-a-Pas" community intervention trial.
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DOI：
10.1186/s12889-017-4485-3
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发表时间：
2017-06-15
影响因子：
4.5
通讯作者：
Pas-a-Pas research group
中科院分区：
文献类型：
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作者：
Arija V;Villalobos F;Pedret R;Vinuesa A;Timón M;Basora T;Aguas D;Basora J;Pas-a-Pas research group
体力活动是心血管疾病（CVD）的主要、可改变的风险因素，有助于预防和管理CVD。本研究的目的是评估为期9个月的有监督的身体活动计划（包括社会文化活动）对成年人CVD风险的短期和中期有效性。多中心、随机、对照社区干预，涉及4个初级保健中心的364例患者。参与者被随机分配到对照组（CG = 104）或干预组（IG = 260）;平均年龄65.19岁; 76.8%为女性。干预包括每周120分钟的步行（396 MET/分钟/周）和每月一次的社会文化聚会。在基线和干预结束时评估临床病史、体力活动、饮食摄入、CVD风险因素（吸烟、收缩压和舒张压、体重、腰围、BMI、总胆固醇、LDL-和HDL-胆固醇、甘油三酯、糖化血红蛋白和葡萄糖）和总体CVD风险，并将多变量模型应用于数据。在干预后2年评估不良心血管事件的发生率和对体力活动的持续坚持。在干预期结束时，IG组相对于CG组，体力活动显著增加（774.81 MET/min/周），即使在调整潜在混杂因素后，收缩压（−6.63 mmHg）、总胆固醇（−10.12 mg/dL）和LDL-胆固醇（−9.05 mg/dL）在干预期间也发生了显著变化。干预后2年，与对照组相比，IG中不良心血管事件的发生率显著降低（2.5% vs 10.5%），IG中坚持定期体力活动的比例高于对照组（72.8% vs 27.2%）。这项以社区为基础的体育活动计划在短期和中期改善了心血管健康，并在中期促进了西班牙老年人的定期体育活动。 Clinicaltrials.gov ID NCT02767739。试验于2016年5月5日注册。追溯登记
Physical activity is a major, modifiable, risk factor for cardiovascular disease (CVD) that contributes to the prevention and management of CVD. The aim of this study was to assess the short- and medium-term effectiveness of 9 months of a supervised physical activity program, including sociocultural activities, on CVD risk in adults. Multicentered, randomized, controlled community intervention involving 364 patients in four primary care centers. The participants were randomly assigned to a Control Group (CG = 104) or Intervention Group (IG = 260); mean age 65.19 years; 76.8% women. The intervention consisted of 120 min/week walking (396 METs/min/week) and sociocultural gathering once a month. Clinical history, physical activity, dietary intake, CVD risk factors (smoking, systolic and diastolic blood pressure, weight, waist circumference, BMI, total cholesterol, LDL- and HDL-cholesterol, triglycerides, glycosylated hemoglobin and glucose) and global CVD risk were assessed at baseline and at the end of the intervention and multivariate models were applied to the data. Incidence of adverse cardiovascular events and continued adherence to the physical activity were assessed 2 years after intervention. At the end of the intervention period, in the IG relative to the CG group, there was a significant increase in physical activity (774.81 METs/min/week), a significant change during the intervention period in systolic blood pressure (−6.63 mmHg), total cholesterol (−10.12 mg/dL) and LDL-cholesterol (−9.05 mg/dL) even after adjustment for potential confounders. At 2 years after the intervention, in the IG, compared with the CG, tthe incidence of adverse cardiovascular events was significantly lower (2.5% vs. 10.5%) and the adherence to regular physical activity was higher (72.8% vs 27.2%) in IG compared to CG. This community-based physical activity program improved cardiovascular health in the short- as well as medium-term, and promoted regular physical activity in the medium-term in older Spanish adults. Clinicaltrials.gov ID NCT02767739. Trial registered on May 5th, 2016. Retrospectively registered