Synthesis and properties of 8α‐substituted riboflavins of biological importance

Synthesis and properties of 8α‐substituted riboflavins of biological importance
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具有生物学重要性的8α-取代核黄素的合成和性质

DOI:
10.1016/0014-5793(72)80091-7
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发表时间:
1972
期刊:
影响因子:
3.5
通讯作者:
W. H. Walker
W. H. Walker
中科院分区:
生物学3区
文献类型:
--
作者:
W. Kenney;W. H. Walker

文献摘要

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在过去的3年中,两种类型的黄素辅基共价连接到蛋白质的结构已被阐明。在每种情况下,辅酶都是通过黄素的8位连接的(参见。方案1)与氨基酸的官能团。在呼吸酶琥珀酸脱氢酶中,FAD共价结合
Within the last 3 yr the structures of 2 types of flavin prosthetic groups covalently linked to proteins have been elucidated. In each case the co-enzyme is linked through the 8wposition of flavin (cf. scheme 1) to functional groups of amino acids. In the respiratory enzyme, succinate dehydrogenase, FAD is covalently