Full-wave modeling of therapeutic ultrasound: Nonlinear ultrasound propagation in ideal fluids
Full-wave modeling of therapeutic ultrasound: Nonlinear ultrasound propagation in ideal fluids
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DOI：
10.1121/1.1468876
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发表时间：
2002-05-01
影响因子：
2.4
通讯作者：
Ridelinger, RE
中科院分区：
文献类型：
--
作者：
Ginter, S;Liebler, M;Ridelinger, RE
用于治疗目的的高强度聚焦超声的应用数量正在增长。除了碎石术等已建立的应用外，还出现了整形外科或肿瘤治疗中的新应用，如超声。因此，必须开发新的装置，其提供专门用于应用的聚焦区中的压力波形和分布。在本文中，提出了一种非线性降波仿真模型，该模型预测了给定换能器和初始压力信号的所产生的超声场的治疗重要特性。一个非线性声学近似的守恒形式的原始流体动力学方程的理想流体，而不是一个波动方程提供了基础的非线性模型。该方程是用显式高阶时域有限差分算法实现的。根据色散关系保持方法导出了必要的系数。模拟结果为两种不同的治疗换能器：自聚焦压电和反射器聚焦。通过与解析解和实测值的比较，验证了计算结果的正确性。模拟和实验结果之间的协议约10%。(C)2002年美国声学学会。
The number of applications of high-intense, focused ultrasound for therapeutic purposes is growing. Besides established applications like lithotripsy, new applications like ultrasound in orthopedics or for the treatment of tumors arise. Therefore, new devices have to be developed which provide pressure waveforms and distributions in the focal zone specifically for the application. In this paper, a nonlinear fall-wave simulation model is presented which predicts the therapeutically important characteristics of the generated ultrasound field for a given transducer and initial pressure signal. A nonlinear acoustic approximation in conservation form of the original hydrodynamic equations for ideal fluids rather than a wave equation provides the base for the nonlinear model. The equations are implemented with an explicit high-order finite-difference time-domain algorithm. The necessary coefficients are derived according to the dispersion relation preserving method. Simulation results are presented for two different therapeutic transducers: a self-focusing piezoelectric and one with reflector focusing. The computational results are validated by comparison with analytical solutions and measurements. An agreement of about 10% is observed between the simulation and experimental results. (C) 2002 Acoustical Society of America.