Cobalt nitride nanowire array as an efficient electrochemical sensor for glucose and H2O2 detection
Cobalt nitride nanowire array as an efficient electrochemical sensor for glucose and H2O2 detection
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DOI：
10.1016/j.snb.2017.08.098
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发表时间：
2018-02
影响因子：
8.4
通讯作者：
Fengyu Xie;Fengyu Xie;Xiaoqin Cao;Xiaoqin Cao;Fengli Qu;Abdullah M. Asiri;Xuping Sun
中科院分区：
文献类型：
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作者：
Fengyu Xie;Fengyu Xie;Xiaoqin Cao;Xiaoqin Cao;Fengli Qu;Abdullah M. Asiri;Xuping Sun
由于其比表面积大且易于接近目标分子，开发非贵金属纳米阵列结构作为用于分子检测的高活性催化剂电极非常有吸引力。在本文中，我们展示了钛网上氮化钴纳米线阵列（Co3N NW/TM）的开发，作为一种有效的催化剂电极，用于碱性溶液中的葡萄糖氧化和中性溶液中的H2O2还原。电化学测试表明，这种 Co3N NW/TM 对快速葡萄糖和 H2O2 检测具有优异的非酶传感能力。作为葡萄糖传感器，该电极具有 3325.6 μA mM−1cm−2 的高灵敏度、0.1 μM 至 2.5 mM 的宽线性范围、50 nM (S/N = 3) 的低检测限以及令人满意的稳定性和重现性。其在测定人血清中的葡萄糖方面的应用也取得了成功。电流法 H2O2 传感也可以实现，灵敏度为 139.9 μA mM−1cm−2，线性范围为 2 μM 至 28 mM，检测限为 1 μM (S/N = 3)。这种纳米阵列结构作为电化学小分子检测的有吸引力的传感平台具有巨大的前景。
It is highly attractive to develop non-noble-metal nanoarray architecture as a high-active catalyst electrode for molecular detection due to its large specific surface area and easy accessibility to target molecules. In this paper, we demonstrate the development of cobalt nitride nanowire array on Ti mesh (Co3N NW/TM) as an efficient catalyst electrode for glucose oxidation in alkaline solutions and H2O2reduction in neutral solutions. Electrochemical tests suggest that such Co3N NW/TM possesses superior non-enzymatic sensing ability toward rapid glucose and H2O2detection. As a glucose sensor, this fabricated electrode offers a high sensitivity of 3325.6 μA mM−1cm−2, with a wide linear range from 0.1 μM to 2.5 mM, a low detection limit of 50 nM (S/N = 3), and satisfactory stability and reproducibility. Its application in determining glucose in human blood serum is also successful. Amperometric H2O2sensing can also been realized with a sensitivity of 139.9 μA mM−1cm−2, a linear range from 2 μM to 28 mM, and a detection limit of 1 μM (S/N = 3). This nanoarray architecture holds great promise as an attractive sensing platform toward electrochemical small molecules detection.