A Distance-Controlled Nanoparticle Array Using PEGylated Ferritin
A Distance-Controlled Nanoparticle Array Using PEGylated Ferritin
复制标题
使用聚乙二醇化铁蛋白的距离控制纳米颗粒阵列
DOI：
10.1088/2053-1591/1/4/045410
复制
发表时间：
2014
影响因子：
2.3
通讯作者：
and Yukiharu Uraoka
中科院分区：
文献类型：
--
作者：
Chao He;Mutsunori Uenuma;Naofumi Okamoto;Hiroki Kamitake;Yasuaki Ishikawa;Ichiro Yamashita;and Yukiharu Uraoka
采用简单的旋涂法制备了一种间距可控的纳米粒子阵列。结果发现，通过使用聚乙二醇（PEG），纳米粒子的分离距离被控制在纳米级。铁蛋白被用来合成纳米颗粒，并通过使用不同分子量的PEG将它们携带到基底上。为了控制NP的距离，将分子量为2k、5 k、10 k和20 k的PEG以10 mM离子强度和0.01mg ml-1铁蛋白浓度修饰在铁蛋白上。随着PEG分子量的增加，纳米粒子的间距沿着增加。
A distance-controlled nanoparticle (NP) array was investigated using a simple spin coating process. It was found that the separation distance of NPs was controlled at the nanoscale by using polyethylene glycols (PEGs). Ferritin was used to synthesize NPs and carry them to a substrate by using the different molecular weight of PEGs. In order to control the distance of the NPs, PEGs with molecular weights of 2k, 5k, 10k and 20k were modified on ferritin with 10 mM ion strength and 0.01 mg ml− 1 ferritin concentration. The separated distances of NPs increased along with increase in PEG molecular weight.