LABORATORY TESTS FOR PNEUMONIA IN GENERAL PRACTICE THE DIAGNOSTIC VALUES DEPEND ON THE DURATION OF ILLNESS
LABORATORY TESTS FOR PNEUMONIA IN GENERAL PRACTICE THE DIAGNOSTIC VALUES DEPEND ON THE DURATION OF ILLNESS
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DOI：
10.3109/02813439209014067
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发表时间：
1992-01-01
影响因子：
2.1
通讯作者：
BROX J
中科院分区：
文献类型：
--
作者：
MELBYE H;STRAUME B;BROX J
本文对402例成人呼吸道感染患者的体温、血沉（ESR）、白细胞计数和C反应蛋白（CRP）等实验室检查与X线检查进行了对比，评价了体温对肺炎的诊断价值。20例患者诊断为放射学肺炎。CRP和ESR是最有用的检查。CRP > 50 mg/l的敏感性和似然比（LR）较低，分别为0.50和4.8。在病程超过6天的患者中，相应的LR为11.3，这是由于该亚组患者的特异性较高。ESR和口腔温度在这个亚组中也比在病程较短的患者中更有用。Logistic回归分析表明，在病史和体格检查中加入ESR和CRP具有非常显著的诊断作用，特别是当疾病持续一周或更长时间时。
The usefulness in the diagnosis of pneumonia of temperature and the laboratory tests: erythrocyte sedimentation rate (ESR), leucocyte count, and C-reactive protein (CRP) was evaluated against a radiographic reference standard in 402 adult patients with respiratory tract infection in general practice. Radiographic pneumonia was diagnosed in 20 patients. CRP and ESR were the most useful tests. CRP > 50 mg/l had lower sensitivity and likelihood ratio (LR), 0.50 and 4.8, respectively, compared with previous studies of selected patient populations. Among patients whose duration of illness exceeded six days the corresponding LR was 11.3, due to a higher specificity in this subgroup of patients. ESR and oral temperature were also more useful in this subgroup than in patients with a shorter duration of illness. A highly significant diagnostic contribution of adding ESR and CRP to history and physical examination, particularly when the illness had lasted one week or more, was demonstrated by logistic regression.