Fully automated system for three-dimensional bronchial morphology analysis using volumetric multidetector computed tomography of the chest.
Fully automated system for three-dimensional bronchial morphology analysis using volumetric multidetector computed tomography of the chest.
复制标题
使用胸部体积多探测器计算机断层扫描进行三维支气管形态分析的全自动系统。
DOI：
10.1007/s10278-005-9240-0
复制
发表时间：
2006
影响因子：
4.4
通讯作者：
Robinson,TerryE
中科院分区：
文献类型：
--
作者：
Venkatraman,Raman;Raman,Raghav;Raman,Bhargav;Moss,RichardB;Rubin,GeoffreyD;Mathers,LawrenceH;Robinson,TerryE
计算机断层扫描（CT）的最新进展使定量评估慢性肺疾病大气道损伤的严重程度和进展成为可能。快速多探测器计算机断层扫描的出现允许采集快速、低剂量的3D肺容积扫描，这些扫描非常详细地描绘了支气管树。容积CT允许计算支气管气道形态的定量指数，包括气道直径、壁厚、壁面积、气道段长度、气道锥度指数和气道分支模式。然而，支气管树的复杂性和尺寸使得手动测量方法不切实际且不准确。我们已经开发了一个集成的软件包，利用一种新的测量算法称为镜像高斯拟合，使用户能够执行自动支气管分割，测量和数据库存档的支气管形态在高分辨率和容积CT扫描，也允许三维定位，可视化和注册。
Recent advancements in computed tomography (CT) have enabled quantitative assessment of severity and progression of large airway damage in chronic pulmonary disease. The advent of fast multidetector computed tomography scanning has allowed the acquisition of rapid, low-dose 3D volumetric pulmonary scans that depict the bronchial tree in great detail. Volumetric CT allows quantitative indices of bronchial airway morphology to be calculated, including airway diameters, wall thicknesses, wall area, airway segment lengths, airway taper indices, and airway branching patterns. However, the complexity and size of the bronchial tree render manual measurement methods impractical and inaccurate. We have developed an integrated software package utilizing a new measurement algorithm termed mirror-image Gaussian fit that enables the user to perform automated bronchial segmentation, measurement, and database archiving of the bronchial morphology in high resolution and volumetric CT scans and also allows 3D localization, visualization, and registration.