A latent class analysis of psychosis-like experiences in the New Zealand Mental Health Survey

A latent class analysis of psychosis-like experiences in the New Zealand Mental Health Survey
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DOI:
10.1111/j.1600-0447.2011.01707.x
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发表时间:
2011-09-01
影响因子:
6.7
通讯作者:
Browne, M. A. Oakley
Browne, M. A. Oakley
中科院分区:
医学1区
文献类型:
--
作者:
Gale, C. K.;Wells, J. E.;Browne, M. A. Oakley

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目的:描述新西兰心理健康调查中精神病样经历的潜在结构。方法:对16岁以上的家庭居民进行全国性调查(n=7435),使用综合国际诊断性访谈(3.0),包括六个问题的终生精神病筛查。受试者通过三种方式进行分组:根据症状的数量(出现在不做梦、半睡或药物影响下)和根据二元反应(否/是)或顺序反应(从不/低于阈值/几次/多次)得出的潜在类别进行分组。结果:精神病样事件并不少见(7.3%;95%的cis 6.5-8.1),特别是视觉(5.3%;95%的cis 4.7-6.0)或幻听(2.8%;95%的cis 2.3-3.3)。两个潜在类别的分析都表明,这是一个“正常”类别、一个“幻觉类别”和一个“精神病”类别。焦虑、情绪或物质障碍的终生概率和因精神健康问题而寻求帮助的终生概率从“正常”到“幻觉”再到“精神病”类别,并随着“症状”的计数而增加。结论:亚阈值事件的出现和经历“症状”的次数的变化表明精神疾病是一个连续体。然而,被标记为“幻觉的”和“精神病的”的潜在类别在症状学上有明显的不同,这表明了某种形式的离散聚集。
Objective: To describe the underlying structure of psychosis-like experiences in the New Zealand Mental Health Survey.Method: A nationwide survey of household residents aged 16+ years was undertaken (n = 7435), using the Composite International Diagnostic Interview (3.0), including a six question lifetime screener for psychosis. Participants were grouped in three ways: by the number of 'symptoms' (occurring when not dreaming, half-asleep or under the influences of drugs) and by latent classes derived from binary responses (no/yes) or ordinal responses (never/sub-threshold/few times/many times).Results: Psychosis-like events were not uncommon (7.3%; 95% CIs 6.5-8.1), particularly experiences of visual (5.3%; 95% CIs 4.7-6.0) or auditory hallucinations (2.8%; 95% CIs 2.3-3.3). Both latent class analyses indicated a 'normal' class, a 'hallucinatory class' and a 'psychotic' class. The lifetime probability of anxiety, mood or substance disorders and the lifetime probability of seeking help for mental health problems increased from 'normal' to 'hallucinatory' to 'psychotic' classes and with the 'symptom' count.Conclusion: The presence of sub-threshold events and variation in the number of times a 'symptom' is experienced suggest a psychosis continuum. However, the latent classes labelled 'hallucinatory' and 'psychotic' differ markedly in symptomatology, which suggests some form of discrete clustering.