The mechanism of crossing-over IV
The mechanism of crossing-over IV
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DOI：
10.1086/279553
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发表时间：
1916-01-01
影响因子：
2.9
通讯作者：
Muller, HJ
中科院分区：
文献类型：
--
作者：
Muller, HJ
这些数字表示因子与该线中第一个黄色的距离，并且仅仅通过将中间距离相加来计算。这张图给出的不同基因座之间的距离比例几乎与其他工作者通过连锁实验得到的结果完全相同，在连锁实验中，通常一次只继承了两三个因素。因此，每一组比率都证实了另一组比率的准确性。然而，目前地图上的绝对距离较短，是合成地图上的距离的69倍。这主要是由少数雌性产生的非杂交数量较多造成的；在其他情况下，交叉频率大致正常。因此，可以得出结论，就交叉而言，在11对因素方面不同的染色体与除了两个因素外相同的染色体表现方式相同。这与庞尼特的建议相反。此外，在许多因素上不同的染色体表现正常的事实在这里特别值得注意，因为12个隐性因素中有11个在同一条染色体上。
The figures represent the distances of the factors from yellow, the first one in the line, and are calculated merely by adding together the intermediate distances. This map gives almost exactly the same proportionate distances between the different loci as does that obtained by combining, the results of linkage experiments performed by other workers, in which usually the inheritance of only two or three factors was followed at one time. Each set of ratios, therefore, confirms the ace-uracy of the other. The absolute distances in the present map are, however, somewhat shorter, being 69 the length of those in the composite map. This was caused mainly by the comparatively large number of non-cross-overs produced by a few females; in the rest, the crossing-over frequencies were about normal. It may, therefore, be concluded that chromosom-es which differ in regard to eleven pairs of factors behave in the sante way, so far as crossing-over is concerned, as those which are alike except for two factors. This is contrary to a suggestion made by Punnett. Moreover, the fact that chromosomes differing in so many factors behave normally is here especially noteworthy, because 11 of the 12 recessive factors were in the same chromosome.