THE ASSOCIATION BETWEEN MIDLIFE BLOOD-PRESSURE LEVELS AND LATE-LIFE COGNITIVE FUNCTION - THE HONOLULU-ASIA AGING STUDY
THE ASSOCIATION BETWEEN MIDLIFE BLOOD-PRESSURE LEVELS AND LATE-LIFE COGNITIVE FUNCTION - THE HONOLULU-ASIA AGING STUDY
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DOI：
10.1001/jama.274.23.1846
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发表时间：
1995-12-20
影响因子：
120.7
通讯作者：
HAVLIK, RJ
中科院分区：
文献类型：
--
作者：
LAUNER, LJ;MASAKI, K;HAVLIK, RJ
客观。-评估中年血压水平与晚年认知功能的长期关系。在1991年至1993年，对4678名存活的前瞻性檀香山心脏计划（基线，1965-1968年）队列成员进行了第四次检查，并进行了认知测试。研究对象为居住在夏威夷社区或机构的3735名日裔美国男性，第四次检查时平均年龄为78岁。通过100分认知能力筛选量表（CASI）测量的认知功能被分为良好（参考：CASI评分为92至100）、中等（
Objective.-To assess the long-term relationship of midlife blood pressure levels to late-life cognitive function.Design.-The 4678 surviving cohort members of the prospective Honolulu Heart Program (baseline, 1965-1968) were examined a fourth time in 1991 through 1993 and given a cognitive test.Participants.-The subjects were 3735 Japanese-American men living in Hawaii in the community or in institutions, with an average age of 78 years at the fourth examination.Main Outcome Measures.-Cognitive function, measured by the 100-point Cognitive Abilities Screening Instrument (CASI), was categorized into good (reference: a CASI score of 92 to 100), intermediate (