Hydrogen sulfide exposure in an adult male
Hydrogen sulfide exposure in an adult male
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DOI：
10.5144/0256-4947.59379
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发表时间：
2010-01-01
影响因子：
1.6
通讯作者：
Al-Tawfiq, Jaffar A.
中科院分区：
文献类型：
--
作者：
Doujaiji, Bassam;Al-Tawfiq, Jaffar A.
硫化氢（H2S）是许多职业性有毒暴露事件的原因，特别是在石油工业中. H2S的临床效应取决于其浓度和暴露时间.当浓度超过百万分之500-1000（ppm）时，H2 S立即致命，但暴露于较低浓度（如10-500 ppm）时，可引起从鼻炎到急性呼吸衰竭的各种呼吸道症状。H2S还可影响多个器官，导致神经、心血管、肾、肝和血液系统暂时或永久性紊乱。我们提出一个案例，职业暴露于硫化氢导致多器官受累，急性呼吸衰竭，机化性肺炎，休克类似急性败血症。患者还出现轻度阻塞性和限制性肺病和周围神经病变。
Hydrogen sulfide (H 2 S) is responsible for many incidents of occupational toxic exposure, especially in the petroleum industry. The clinical effects of H 2 S depend on its concentration and the duration of exposure. H 2 S is immediately fatal when concentrations are over 500-1000 parts per million (ppm) but exposure to lower concentrations, such as 10-500 ppm, can cause various respiratory symptoms that range from rhinitis to acute respiratory failure. H 2 S may also affect multiple organs, causing temporary or permanent derangements in the nervous, cardiovascular, renal, hepatic, and hematological systems. We present a case of occupational exposure to H 2 S leading to multi-organ involvement, acute respiratory failure, organizing pneumonia, and shock resembling acute sepsis. The patient also developed mild obstructive and restrictive pulmonary disease and peripheral neuropathy.