Epidemiology of hypertension and chronic kidney disease in China.
Epidemiology of hypertension and chronic kidney disease in China.
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DOI：
10.1097/mnh.0b013e328337f921
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发表时间：
2010-05
影响因子：
3.2
通讯作者：
Chen J
中科院分区：
文献类型：
--
作者：
Chen J
高血压和慢性肾脏病已成为中国主要的公共卫生挑战。据估计，2002年约有1.53亿中国成年人患有高血压。据估计，2005年中国有233万心血管死亡和127万心血管过早死亡可归因于血压升高。大约39%的中国成年人对膳食钠摄入高度敏感，这是高血压和心血管疾病的危险因素。由于研究人群和慢性肾脏疾病定义的差异，不同研究中慢性肾脏疾病的患病率差异很大。一项大型前瞻性队列研究估计，在40岁及以上的中国成年人中，终末期肾病的发病率和死亡率分别为30.7/10万人-年和20.9/10万人-年。高血压和代谢综合征已被证明是慢性肾脏疾病的危险因素。此外，体重与终末期肾病发生率之间呈J形相关，饮酒与终末期肾病风险之间呈负相关。这些结果强调迫切需要制定预防，检测和治疗高血压和慢性肾脏疾病的国家战略。
Hypertension and chronic kidney disease have become major public health challenges in China. It is estimated that approximately 153 million Chinese adults had hypertension in 2002. It is also estimated that 2.33 million total cardiovascular deaths and 1.27 million premature cardiovascular deaths were attributable to increased blood pressure in 2005 in China. Approximately 39% of Chinese adult populations are highly sensitive to dietary sodium intake, a risk factor for hypertension and cardiovascular disease. The prevalence of chronic kidney disease varied greatly among studies due to differences in study populations and definitions of chronic kidney disease. A large prospective cohort study estimates that incidence and mortality of end-stage renal disease was 30.7 and 20.9 per 100,000 person-years among Chinese adults aged 40 years and older. Hypertension and the metabolic syndrome have been documented as risk factors for chronic kidney disease. In addition, a J-shaped association between body weight and incidence of end-stage renal disease and an inverse association between alcohol consumption and risk of end-stage renal disease were documented. These results underscore the urgent need to develop national strategies for the prevention, detection, and treatment of hypertension and chronic kidney disease.