Vibration perception threshold testing in patients with diabetic neuropathy: ceiling effects and reliability
Vibration perception threshold testing in patients with diabetic neuropathy: ceiling effects and reliability
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DOI：
10.1046/j.1464-5491.2001.00503.x
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发表时间：
2001-06-01
影响因子：
3.5
通讯作者：
Cavanagh, PR
中科院分区：
文献类型：
--
作者：
van Deursen, RWM;Sanchez, MM;Cavanagh, PR
目的 测试新型振动计 (Maxivibrometer) 的可靠性，该振动计的构建可以确定振动感知阈值 (VPT)，而不会出现生物振动计经常出现的超量程测量的缺点。 方法 在一组糖尿病神经病变受试者和一组健康、匹配的对照受试者上对这两种设备进行比较和测试。 VPT 在足底表面进行测试。结果 即使受试者患有严重的神经病，Maxivibrometer 在所有情况下都能给出实际测量结果。除一例外，Maxivibrometer VPT 的复制间相关系数和日常组内相关系数均高于 0.94，表明具有出色的可靠性。生物感觉计 VPT 的测量也具有出色的可靠性，但仅限于轻度至中度神经病变的有限范围内，因此它似乎是一种合适的筛查工具。复制间的组内相关系数为 0.93。结论 由于使用 Maxivibrometer 可以在很宽的范围内测量 VPT，因此证明糖尿病神经病变中的感觉丧失可能会远远超出生物振动计的最大 VPT 值。宽广的测量范围和卓越的可靠性使Maxivibrometer成为一种有价值的研究工具，可量化感觉丧失，特别是在存在严重神经病变的情况下，并记录随时间的变化。
Aims To test the reliability of a new vibrometer (Maxivibrometer) which was constructed so that vibration perception threshold (VPT) could be determined without the disadvantage of the off-scale measurements frequently experienced with the Biothesiometer.Methods The two devices were compared and tested on a group of diabetic neuropathic subjects and a group of healthy, matched control subjects. VPT was tested on the plantar surface of the feet.Result The Maxivibrometer gave an actual measurement in all cases even if subjects were severely neuropathic. The replication-to-replication and day-to-day intraclass correlation coefficients for the Maxivibrometer VPT were, except in one case, above 0.94, indicating excellent reliability. The Biothesiometer VPT could also be measured with excellent reliability but only within a limited range of mild to moderate neuropathy, so it appears to be an appropriate screening tool. The replication-to-replication intraclass correlation coefficient was 0.93.Conclusions Because VPT could be measured over a wide range with the Maxivibrometer, it was demonstrated that loss of sensation in diabetic neuropathy can progress far beyond the maximum VPT value of the Biothesiometer. The wide measurement range and the excellent reliability make the Maxivibrometer a valuable research tool to quantify loss of sensation, particularly in the presence of severe neuropathy and to record changes over time.