MERSACIDIN, A NEW ANTIBIOTIC FROM BACILLUS FERMENTATION, ISOLATION, PURIFICATION AND CHEMICAL CHARACTERIZATION
MERSACIDIN, A NEW ANTIBIOTIC FROM BACILLUS FERMENTATION, ISOLATION, PURIFICATION AND CHEMICAL CHARACTERIZATION
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DOI：
10.7164/antibiotics.45.832
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发表时间：
1992-06-01
影响因子：
3.3
通讯作者：
KOGLER, H
中科院分区：
文献类型：
--
作者：
CHATTERJEE, S;CHATTERJEE, S;KOGLER, H
美沙菌素(1)是一种含有β-甲基绵羊硫氨酸的新型多肽抗生素。它被归类为建议的抗生素类中的一员，由一种芽孢杆菌产生。美沙星分子量为1,824(C80H120N20O21S4)。这种抗生素对革兰氏阳性菌包括耐甲氧西林金黄色葡萄球菌有活性，但对革兰氏阴性菌或真菌没有活性。
Mersacidin (1) is a new peptide antibiotic containing beta-methyllanthionine. It is classified as a member of the proposed lantibiotic group of antibiotics, and is produced by a species of Bacillus. Mersacidin has a molecular weight of 1,824 (C80H120N20O21S4). The antibiotic is active against Gram-positive organisms including methicillin-resistant Staphylococcus aureus, but has no activity against Gram-negative bacteria or fungi.