[Identification of migrants from nitrile-butadiene rubber gloves].
[Identification of migrants from nitrile-butadiene rubber gloves].
复制标题
[丁腈橡胶手套中迁移物的鉴定]。
DOI：
10.3358/shokueishi.44.103
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
T. Maitani
中科院分区：
文献类型：
--
作者：
M. Mutsuga;Y. Kawamura;C. Wakui;T. Maitani
含有邻苯二甲酸二（2-乙基己基）酯的聚氯乙烯手套仅限用于食品接触。取而代之的是由丁腈橡胶（NBR）制成的一次性手套，用于接触食品。发现一些未知物质从NBR手套迁移到正庚烷中。经GC/MS、HR-MS和NMR确证其化学结构为2，2，4-三甲基-1，3-戊二醇二异丁酸酯（用作增塑剂），4，4 '-亚丁基二（6-叔丁基-间甲酚），由2-甲基-间甲酚组成的苯乙烯化苯酚的混合物，（α-甲基苄基）苯酚，4- 2，6-二（α-甲基苄基）苯酚2，4-二（α-甲基苄基）苯酚（α-甲基苄基）苯酚和2，4，6-三（α-甲基苄基）苯酚（用作抗氧化剂）和2，4-二叔丁基苯酚，其似乎是抗氧化剂的降解产物。这些化合物向正庚烷中的迁移水平分别为1.68微克/厘米2的2，4-二叔丁基苯酚、2.80微克/厘米2的2，2，4-三甲基-1，3-戊二醇二异丁酸酯、46.08微克/厘米2的苯乙烯化苯酚和4.22微克/厘米2的4，4 '-亚丁基二（6-叔丁基间甲酚）。在NBR手套中总苯乙烯化酚的含量为6，900微克/克。
Polyvinyl chloride gloves containing di(2-ethylhexyl) phthalate are restricted for food contact use. In their place, disposable gloves made from nitrile-butadiene rubber (NBR) are used in contact with foodstuffs. Some unknown substances were found to migrate into n-heptane from NBR gloves. By GC/MS, HR-MS and NMR, their chemical structures were confirmed to be 2,2,4-trimethyl-1,3-pentanediol diisobutyrate (used as a plasticizer), 4,4'-butylidenedi(6-tert-butyl-m-cresol), a mixture of styrenated phenols consisting of 2-(alpha-methylbenzyl)phenol, 4-(alpha-methylbenzyl)phenol, 2,6-di(alpha-methylbenzyl)phenol, 2,4-di(alpha-methylbenzyl)phenol and 2,4,6-tri(alpha-methylbenzyl)phenol (used as antioxidants), and 2,4-di-tert-butylphenol, which seems to a degradation product of antioxidant. Migration levels of these compounds were 1.68 micrograms/cm2 of 2,4-di-tert-butylphenol, 2.80 micrograms/cm2 of 2,2,4-trimethyl-1,3-pentanediol diisobutyrate, 46.08 micrograms/cm2 of styrenated phenols and 4.22 micrograms/cm2 of 4,4'-butylidenedi(6-tert-butyl-m-cresol) into n-heptane, respectively. The content of total styrenated phenols was 6,900 micrograms/g in NBR gloves.