Determining the solubility and crystal form of clenbuterol in thin films of eudragit NE30D
Determining the solubility and crystal form of clenbuterol in thin films of eudragit NE30D
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测定克伦特罗在尤特奇 NE30D 薄膜中的溶解度和晶型
DOI：
10.3109/03639049209043702
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发表时间：
1992
影响因子：
3.4
通讯作者：
Geoffrey Lee
中科院分区：
文献类型：
--
作者：
A. Göpferich;Geoffrey Lee
已经测量了药物克伦特罗在无表面活性剂的Eudragit NE30D薄膜中的溶解度。光学显微镜和差示扫描量热法的基础上测量的药物从膜释放速率的技术进行了补充。克伦特罗晶体具有分形的形式，正如扩散控制聚集的计算机模拟所示。
The solubility of the drug clenbuterol in thin films of surfactant-free Eudragit NE30D has been measured. Light microscopy and differential scanning calorimetry were supplemented by a technique based on measurement of the rate of drug release from the films. The clenbuterol crystals had the form of a fractal, as could be shown by a computer simulation of diffusion-controlled aggregation.