Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
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DOI：
10.1051/parasite/2003104359
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发表时间：
2003-12-01
期刊：
影响因子：
2.9
通讯作者：
Hougard, JM
中科院分区：
文献类型：
--
作者：
Darriet, F;Corbel, V;Hougard, JM
为了防止冈比亚按蚊对拟除虫菊酯类杀虫剂的抗药性传播过快，并延长浸有杀虫剂的蚊帐的有效性，最近有人建议使用具有不同作用方式的混合杀虫剂。本文介绍了用联苯菊酯（一种拟除虫菊酯）和甲基氯吡虫啉（一种有机磷）单独和混合处理薄纱蚊帐对两种安虫的效果。冈比亚，一种对所有杀虫剂都敏感，另一种对拟除虫菊酯有抗性。联苯菊酯（25 mg/m(2)）和氯吡虫啉（4.5 mg/m(2)）混合药剂的KDt值（50）和KDt值（95）及致死率均表现出显著的协同效应。冈比亚对杀虫剂敏感。然而，试验组合对氯菊酯选择的VKPR菌株没有任何协同作用，而只是提高了两种杀虫剂单独使用的有效性。
In order to prevent the resistance of Anopheles gambiae s.l. to pyrethroids from spreading too quickly and to lengthen the effectiveness of insecticide impregnated mosquito nets, it has recently been suggested to use mixtures of insecticides that have different modes of action. This study presents the results obtained with tulle mosquito nets treated with bifenthrin (a pyrethroid) and chlorpyrifos-methyl (an organophosphorous) both separately and in mixture on two strains of An. gambiae, one sensitive to all insecticides, and the other resistant to pyrethroids. The values of KDt(50) and KDt(95) and the mortality induced with the mixture of bifenthrin (25 mg/m(2)) and chlorpyrifos-methyl (4.5 mg/m(2)) Show a significant synergistic effect on the strain of An. gambiae susceptible to insecticides. However, the tested combination does not induce any synergistic effect on the VKPR strain selected with permethrin, but only enhances the effectiveness of the two insecticides taken separately.