THE EFFECT OF TEMPERATURE ON THE ELECTRICAL ACTIVITY OF THE GIANT AXON OF THE SQUID
THE EFFECT OF TEMPERATURE ON THE ELECTRICAL ACTIVITY OF THE GIANT AXON OF THE SQUID
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DOI：
10.1113/jphysiol.1949.sp004388
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发表时间：
1949-01-01
影响因子：
5.5
通讯作者：
KATZ, B
中科院分区：
文献类型：
--
作者：
HODGKIN, AL;KATZ, B
方法取Forbesi枪乌贼星神经最大轴突（直径500-700）进行实验。Hodgkin & Huxley（1945）和Hodgkin & Katz（1949）描述了纤维的安装、微电极的插入以及记录动作电位和电位变化率的方法。通过更换轴突周围的海水浴（约100 cc）来改变温度，并在靠近神经插入的温度计上读取。温度变化对峰电位和静息电位的影响没有明显的滞后，只要温度不超过350 ℃，此时轴突会逐渐衰竭因此，可以通过使浴槽
METHOD The experiments were made on the largest axon (diameter 500-700,) of the stellar nerve of Loligo forbesi. The mounting of the fibre, insertion of the microelectrode and the method of recording action potentials and rates of potential change have been described by Hodgkin & Huxley (1945) and Hodgkin & Katz (1949). The temperature was varied by replacing the sea water-bath around the axon (about 100 cc) and was read on a thermometer inserted close to the nerve. The effects of temperature change on the spike and resting potential were established without noticeable lag, provided that the tem-perature was not raised much above 350 C., at which point the axons tended to fail progressively. It was, therefore, possible to obtain a continuous range of measurement by allowing the bath to