The Prevalence, Antibiotic Resistance and Biofilm Formation of Staphylococcus aureus in Bulk Ready-To-Eat Foods
The Prevalence, Antibiotic Resistance and Biofilm Formation of Staphylococcus aureus in Bulk Ready-To-Eat Foods
复制标题
散装即食食品中金黄色葡萄球菌的流行率、抗生素耐药性和生物膜形成
DOI：
10.3390/biom9100524
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发表时间：
2019-10-01
期刊：
影响因子：
5.5
通讯作者：
Chi, Yuanlong
中科院分区：
文献类型：
--
作者：
Lin, Qi;Sun, Honghu;Chi, Yuanlong
对2013-2016年四川省2160份散装即食食品中金黄色葡萄球菌的流行情况进行了调查。对该菌的耐药性及其相关基因进行了研究，并对该菌的生物膜形成能力进行了初步探讨。测量金黄色葡萄球菌分离株。并对耐药基因与抗生素耐药性的关系进行了讨论。结果表明，54 S.在肉制品、乳制品、水果蔬菜和甜点中的检出率分别为31（2.6%）、6（3.0%）、9（2.2%）和8（2.3%）。大多数菌株（52/54）对至少一种抗生素耐药，21株被鉴定为多重耐药（MDR）S。金黄色。3株耐甲氧西林的S.金黄色。青霉素、红霉素、克林霉素、四环素和克林霉素诱导型耐药为主要耐药抗生素，对这5种抗生素表型耐药的菌株均检测到耐药相关基因。总共有33个54 S。金黄色葡萄球菌菌株具有生物膜形成能力，包括2株强生物膜形成菌、1株中等生物膜形成菌和30株弱生物膜形成菌。两个S具有较强生物膜形成能力的金黄色葡萄球菌菌株显示出多重耐药性，并且一个中度生物膜产生者对两类抗生素具有耐药性。
The prevalence of Staphylococcus aureus in 2160 bulk ready-to-eat foods from the Sichuan province of China during 2013-2016 was investigated. The antibiotic resistance and the associated genes, as well as biofilm formation capacity of the S. aureus isolates were measured. Furthermore, the relationship between the antibiotic resistance and the resistant genes was discussed. It was found that 54 S. aureus isolates were recovered, and their prevalence in meat products, dairy, fruit and vegetables, and desserts were 31 (2.6%), six (3.0%), nine (2.2%) and eight (2.3%), respectively. Most strains (52/54) were resistant to at least one of the antibiotics, and 21 isolates were identified as multidrug-resistant (MDR) S. aureus. Three isolates were found to be methicillin-resistant S. aureus. Penicillin, erythromycin, clindamycin, tetracycline and inducible clindamycin resistance were determined as the predominant antibiotics, and the isolates with the phenotypic resistance on these five antibiotics were all determined positive for the resistant gene associated. In total, 33 of 54 S. aureus isolates showed biofilm formation capacity, including two strong biofilm producers, one moderate and 30 weak ones. Two S. aureus isolates with strong biofilm formation abilities showed multi-drug resistance, and one moderate biofilm producer was resistant to two categories of antibiotics.