Evo-devo aspects of classical and molecular data in a historical perspective
Evo-devo aspects of classical and molecular data in a historical perspective
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DOI：
10.1002/jez.b.20003
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发表时间：
2004-01-15
影响因子：
2.2
通讯作者：
Schmidt-Ott, U
中科院分区：
文献类型：
--
作者：
Sander, K;Schmidt-Ott, U
我们将讨论自1800年以来反映在数据和概念中的进化与发展之间的相互作用。达尔文和他的“大陆使徒”海克尔把早期脊椎动物胚胎之间惊人的相似性放在了进化的背景下。海克尔部分不正当的概括使早期实验胚胎学家对进化思想失去了信心，他们还指出了与当代同源性和进化概念不相容的谜题。最近的个体发生网络概念提出了相关的解决方案，其中包含复杂的调控特性和部分重叠功能的基因。关于发育的分子数据越来越多地揭示了进化机会主义，例如，在一些进化先进的昆虫群体中，参与原始免疫防御的广泛信号链显然后来被招募用于决定背腹轴。最近，立克次体相关细菌定植在许多节肢动物物种中，被发现“操纵”宿主发育的第一步，以有利于它们自己的繁殖，但也可以通过促进宿主物种形成的方式。分子遗传学现在可以记录个体发生网络中的进化步骤。以果蝇为例，这种新的双头体基因取代了先前存在的网络中一个关键的模式功能——这是一个“分子线虫发生”的例子。保守基因的表达模式，拮抗决定背-腹极性支持字面上的革命设想近200年前。这是一些后生动物身体结构的背-腹倒置，当时被认为是关节目，现在被认为是脊索目。最后一节假定，进化创新的机会主义特征不利于发展中的节俭。(C) 2004 Wiley-Liss, Inc。
We discuss the interplay between evolution and development as reflected in data and concepts since about 1800. Darwin and his "continental apostle" Haeckel put the striking similarity between early vertebrate embryos in an evolutionary context. Haeckel's partly illicit generalizations discredited evolutionary thinking among early experimental embryologists who moreover noted riddles incompatible with contemporary concepts of homology and evolution. Relevant solutions were suggested by the more recent concept of ontogenetic networks that embody complex regulatory properties and genes with partly overlapping functions. Molecular data on development increasingly reveal evolutionary opportunism, for instance when a widespread signaling chain involved in primitive immune defense was apparently recruited later on for dorsoventral axis determination in some evolutionarily advanced insect groups. Recently, Rickettsia-related bacteria colonizing many arthropod species were found to "manipulate" the first steps of host development to the advantage of their own propagation, but by ways that could also promote host speciation. Molecular genetics can now document evolutionary steps in ontogenetic networks. In the fruit fly for instance, the novel bicoid gene has superseded a crucial patterning function within a pre-existing network-a case of "molecular caenogenesis." The expression patterns of conserved genes that antagonistically determine dorso-ventral polarity support a literal revolution envisioned almost 200 years ago. This is the dorso-ventral inversion of the body plan in some metazoans-ascribed then to the Articulata, now to the Chordata. The final section posits that the opportunistic character of evolutionary innovations is detrimental to parsimony in development. (C) 2004 Wiley-Liss, Inc.