Status epilepticus and periictal imaging
Status epilepticus and periictal imaging
复制标题
DOI：
10.1111/j.0013-9580.2004.04014.x
复制
发表时间：
2004-01-01
期刊：
影响因子：
5.6
通讯作者：
Cole, AJ
中科院分区：
文献类型：
--
作者：
Cole, AJ
解剖和功能影像学检查的发作前后变化已被认识多年。随着磁共振成像和正电子发射断层扫描的广泛应用，越来越多的公认的急性影像学表现已被描述。发作期和发作后的结果可以分为本地或远程，相对于最大的发作脑电图异常的网站。虽然所描述的许多发现是可逆的，但决定发现是否会消退的因素尚未完全了解。这篇文章认为，已被描述的结果的范围内，将它们放置到已知的或假设的病理生理机制的背景下，并考虑其临床意义。提出了一个框架，考虑发作持续时间和严重程度之间的关系，成像异常的特点，其潜在的病理生理机制。
Peri- and postictal changes on both anatomic and functional imaging examinations have been recognized for many years. With the wide availability of magnetic resonance imaging and positron emission tomography, a growing range of recognized acute imaging findings have been described. Periictal and postictal findings can be classified as either local or remote, with respect to the site of maximal ictal EEG abnormality. Although many of the findings described are reversible, the factors that determine whether findings will resolve are incompletely understood. This article considers the range of findings that have been described, places them into the context of known or hypothesized pathophysiologic mechanisms, and considers their clinical significance. A framework is proposed for considering the relation between ictal duration and severity, the characteristics of imaging abnormalities, and the mechanism of their underlying pathophysiology.