Mechanical properties of microporous foams of biodegradable plastic
Mechanical properties of microporous foams of biodegradable plastic
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DOI：
10.5004/dwt.2010.1696
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发表时间：
2010-05-01
影响因子：
1.1
通讯作者：
Lloyd, Douglas R.
中科院分区：
文献类型：
--
作者：
Tanaka, Takaaki;Aoki, Takashi;Lloyd, Douglas R.
可生物降解聚酯的渗透性微孔泡沫和膜目前用于组织工程和药物输送系统领域。它们的力学性能在医学应用中是有用的。泡沫塑料应该机械地与植入泡沫的组织相匹配。在这项研究中，我们通过压缩试验研究了生物降解聚酯泡沫塑料的力学性能。采用热诱导相分离法制备了聚L-乳酸、聚己内酯和聚3-羟基丁酸酯-3-羟基戊酸酯微孔泡沫塑料。压缩试验在23-24摄氏度的万能试验机上进行。微孔泡沫的结构取决于聚合物的种类、聚合物浓度和淬火温度。聚合物浓度越高或冷却温度越低，泡沫塑料的泡孔尺寸越小。分析了泡沫材料在压缩试验中的应力-应变图。泡沫塑料与固体材料的相对密度越低，弹性极限应力越小。泡沫塑料的相对杨氏模数和相对弹性极限应力与其相对密度的平方近似成正比，与泡孔尺寸的关系较小。这种依赖关系类似于开孔聚亚安酯泡沫塑料。
Permeable microporous foams and membranes of biodegradable polyesters are currently used in the area of tissue engineering and drug delivery systems. Their mechanical properties are useful in the medical applications. The foams should mechanically fit to the tissues where the foams were implanted. In this study, we investigated the mechanical properties of the foams of biodegradable polyesters by compression tests. Microporous foams of poly(L-lactic acid), poly (epsilon-caprolactone), and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) were prepared by thermally induced phase separation method. The compression tests were performed at 23-24 degrees C with a universal testing machine. The structure of the microporous foams depended on the kinds of polymers, polymer concentrations, and quenching temperatures. The cell size of the foams was smaller when the polymer concentration was higher or the quenching temperature was lower. We analyzed the stress-strain diagrams of the foams in the compression test. The lower the relative density of the foams to the solid materials the lower the elastic limit stress was. The relative Young's modulus and relative elastic limit stress of the foams were approximately proportional to the square of their relative density and less dependent on their cell size. The dependences were similar to those of open-cell foams of polyurethane.