SYNTHESIS OF TELEOCIDIN-A, TELEOCIDIN-B AND THEIR CONGENERS .2. SYNTHESIS OF LYNGBYATOXIN-A (TELEOCIDIN-A-1), TELEOCIDIN-A-2, PENDOLMYCIN, AND (R,E)-7-(3,7,11-TRIMETHYL-1,6,10-DODECATRIEN-3-YL)-(-)-INDOLACTAM-V AND (S,E)-7-(3,7,11-TRIMETHYL-1,6,10-DODECATRIEN-3-YL)-(-)-INDOLACTAM-V
SYNTHESIS OF TELEOCIDIN-A, TELEOCIDIN-B AND THEIR CONGENERS .2. SYNTHESIS OF LYNGBYATOXIN-A (TELEOCIDIN-A-1), TELEOCIDIN-A-2, PENDOLMYCIN, AND (R,E)-7-(3,7,11-TRIMETHYL-1,6,10-DODECATRIEN-3-YL)-(-)-INDOLACTAM-V AND (S,E)-7-(3,7,11-TRIMETHYL-1,6,10-DODECATRIEN-3-YL)-(-)-INDOLACTAM-V
复制标题
DOI：
10.1016/s0040-4020(01)82398-x
复制
发表时间：
1991-09-30
期刊：
影响因子：
2.1
通讯作者：
NATSUME, M
中科院分区：
文献类型：
--
作者：
MURATAKE, H;OKABE, K;NATSUME, M
详细介绍了由(R)-和(S)-甲基N-[7-（3,7-二甲基-1,6-辛二烯-3-基）-4-吲哚基]-N-甲基- l-戊酸盐（3和4）合成肿瘤启动子lyngybyatoxin A (= teleocidin A-1)(1)和teleocidin A-2(2)的方法。其它命名的化合物6,7a和7b以类似方式制备。
Details of the synthesis method of the tumor promoters, lyngbyatoxin A (= teleocidin A-1) (1) and teleocidin A-2 (2) from (R)- and (S)-methyl N-[7-(3,7-dimethyl-1,6-octadien-3-yl)-4-indolyl]-N-methyl-L-valinate (3 and 4) are presented. Other titled compounds, 6, 7a, and 7b, were prepared analogously.