Efficient and regioselective synthesis of functionalized pyrroles by cyclocondensation of 1,3-dicarbonyl dianions with α-azidoketones

Efficient and regioselective synthesis of functionalized pyrroles by cyclocondensation of 1,3-dicarbonyl dianions with α-azidoketones
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DOI:
10.1039/b207840f
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发表时间:
2002-11
影响因子:
4.9
通讯作者:
P. Langer;Ilia Freifeld
P. Langer;Ilia Freifeld
中科院分区:
化学2区
文献类型:
--
作者:
P. Langer;Ilia Freifeld

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1,3-二羰基二离子与α-叠氮酮选择性环缩合得到2-烷基二吡咯烷,经酸处理后转化为功能化吡咯。
The cyclocondensation of 1,3-dicarbonyl dianions with α-azidoketones regioselectively afforded 2-alkylidenepyrrolidines which were transformed into functionalized pyrroles by treatment with acid.