Ni(II) source as a pre-catalyst for the cross-coupling of benzylic pivalates with arylboronic acids: facile access to tri- and diarylmethanes
Ni(II) source as a pre-catalyst for the cross-coupling of benzylic pivalates with arylboronic acids: facile access to tri- and diarylmethanes
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DOI：
10.1039/c4ra16452k
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发表时间：
2015-01-01
期刊：
影响因子：
3.9
通讯作者：
Yang, Lian-Ming
中科院分区：
文献类型：
--
作者：
Chen, Qiang;Fan, Xin-Heng;Yang, Lian-Ming
以Ni（PPh_3）（2）（1-萘基）Cl为预催化剂，在温和条件下，通过新戊酸苄酯与芳基硼酸的Suzuki-Miyaura偶联反应，以较高的产率合成了三芳基甲烷和二芳基甲烷。该方法为合成多芳基甲烷提供了一种廉价、方便、实用的方法。
A simple and easily-used Ni-II complex, Ni(PPh3)(2)(1-naphthyl) Cl, was employed as a pre-catalyst in the Suzuki-Miyaura cross-coupling of benzylic pivalates with arylboronic acids, affording various tri- or diarylmethanes in good yields under mild conditions. This new protocol provides a cheap, convenient and practical alternative to synthesizing multiaryl methanes.