Transient pulmonary eosinophilia incidentally found on low-dose computed tomography: Findings in 40 individuals
Transient pulmonary eosinophilia incidentally found on low-dose computed tomography: Findings in 40 individuals
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DOI：
10.1097/rct.0b013e31806535e5
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发表时间：
2008-01-01
影响因子：
1.3
通讯作者：
Lee, Joo-Hyuk
中科院分区：
文献类型：
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作者：
Kim, Hyae Young;Naidich, David P.;Lee, Joo-Hyuk
目的：描述在低剂量CT （LDCT）上偶然发现的一过性肺嗜酸性粒细胞增多症（TPE）的CT表现，并确定有助于初步诊断的提示性CT特征。材料和方法：我们回顾性回顾了40例符合TPE标准的患者的LDCT扫描结果。男性35例，女性5例（年龄32 ~ 62岁，平均48.5±9岁）。最初的LDCT扫描评估为：(a)结节，进一步表现为实性，实性伴磨玻璃衰减晕，或纯磨玻璃病变，以及数量、大小和位置；或(b)实质实变灶定义不清。结果：发现了一系列局灶性实质异常(n = 78) -单发（48%）和多发（52%）。其中大多数被证实为实性结节，伴有离散的磨玻璃晕（72%），或表现出各种不同形态的界限不清的实性结节（24%）。3例（4%）实变灶不明确。病变主要位于肺下区（73%），周围分布（92%）。结论：短暂性肺嗜糖症最常表现为实性结节伴磨玻璃晕。对TPE的认识有助于减少早期肺癌的误诊。
Purpose: To describe computed tomography (CT) findings of transient pulmonary eosinophilia (TPE) incidentally found on low-dose CT (LDCT) and to identify suggestive CT features helpful in initial diagnosis.Materials and Methods: We retrospectively reviewed LDCT scans in 40 individuals who met criteria for having TPE. There were 35 men and 5 women (age range, 32-62 years; mean, 48.5 +/- 9 years). Initial LDCT scans were assessed as either (a) nodules, further characterized as either solid, solid associated with a halo of ground-glass attenuation, or pure ground-glass lesions as well as by number, size, and location or (b) ill-defined foci of parenchymal consolidation.Results: A range of focal parenchymal abnormalities (n = 78) were identified-both single (48%) and multiple (52%). Most of these proved to be either solid nodules with discrete ground-glass halos (72%), or poorly defined solid nodules exhibiting a variety of differing morphologies (24%). Ill-defined foci of consolidation were noted in 3 cases (4%). The lesions were predominantly located in the lower lung zone (73%) with peripheral distribution (92%).Conclusions: Transient pulmonary cosinophilia most often manifests as solid nodules with associated ground-glass halos. Awareness of TPE should serve to limit the number of mistaken diagnoses of early lung cancer.