Brain control of the lower urinary tract
Brain control of the lower urinary tract
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DOI：
10.1080/003655902320765908
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发表时间：
2002-01-01
影响因子：
--
通讯作者：
Blok, BFM
中科院分区：
文献类型：
--
作者：
Blok, BFM
近十年来，对排尿和排尿神经通路的认识有了很大的扩展。本综述的目的是总结从动物和人体实验中获得的结果，并讨论相关的泌尿系统功能障碍的病理生理学。哺乳动物神经系统的四个特定部分对于排尿和排尿的控制是重要的：1）膀胱壁中的神经节细胞和交感链（自主）和背根链（感觉）; 2）尾侧脊髓中的运动神经元和感觉中间神经元; 3）尾侧脑干和4）皮质和皮质下区域。部分1）至3）包括排尿反射的基本成分，并通过外周神经和中央纤维束相互连接。正常情况下，我们是大陆的尿液不断，除了必要的排空膀胱五至八次一天。神经通路的特定病变可导致不同类型的泌尿功能障碍：排尿或排尿通路的活动减退或活动过度。以及排尿开始时的失控。
The knowledge on neural pathways involved in micturition and continence has been expanded greatly the last ten years. The aim of the present review is to summarize results obtained from animal and human experiments and to discuss the pathophysiology of relevant urological dysfunction. Four specific parts of the mammalian neural system are important for the control of micturition and continence: 1) ganglion cells in the bladder wall and sympathetic chain (autonomic) and dorsal root chain (sensory); 2) motoneurons and sensory interneurons in the caudal spinal cord: 3) the caudal brainstem and 4) the cortical and subcortical areas. The parts 1) to 3) comprise the basic components of the micturition reflex and are interconnected via peripheral nerves and central fiber tracts. Normally, we are continent for urine continuously, except for the necessary emptying of the bladder five to eight times a day. Specific lesions of the neural pathways can result in distinct types of urological dysfunction: hypoactivity or hyperactivity of the micturition or continence pathways. and a loss of control of the beginning of micturition.