Lack of effect of entorhinal kindling on L-[3H]glutamic acid presynaptic uptake and postsynaptic binding in hippocampus.
Lack of effect of entorhinal kindling on L-[3H]glutamic acid presynaptic uptake and postsynaptic binding in hippocampus.
复制标题
内嗅点燃对海马 L-[3H]谷氨酸突触前摄取和突触后结合缺乏影响。
DOI：
10.1016/0014-4886(85)90264-x
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发表时间：
1985
影响因子：
5.3
通讯作者：
Ferrara,LP
中科院分区：
文献类型：
--
作者：
Slevin,JT;Ferrara,LP
在给予电休克癫痫发作或通过内嗅皮层刺激点燃至5级癫痫发作的大鼠海马膜中测量钠非依赖性l-[3 H]谷氨酸结合和钠依赖性l-[3 H]谷氨酸高亲和力摄取。在电休克、点燃或手术对照动物中，这些突触标记物无差异。内嗅点燃不是活动调节的贯穿通路介导物质能神经传递的反应。
Sodium-independentl-[3H]glutamic acid binding and sodium-dependentl-[3H]glutamic acid high affinity uptake were measured in hippocampal membranes of rats administered electroshock seizures or kindled to class 5 seizures by entorhinal cortical stimulation. There were no differences in these glutamatergic synaptic markers among electroshocked, kindled, or surgical control animals. Entorhinal kindling is not a reflection of activity-regulated facilitation of perforant path glutamatergic neurotransmission.