THE PEROXIDASE REACTION IN EPIDEMIC ENCEPHALITIS: A NEW DIAGNOSTIC AND PROGNOSTIC METHOD
THE PEROXIDASE REACTION IN EPIDEMIC ENCEPHALITIS: A NEW DIAGNOSTIC AND PROGNOSTIC METHOD
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流行性脑炎的过氧化物酶反应：一种新的诊断和预后方法
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通讯作者：
Shiro Yoshimatsu
中科院分区：
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作者：
A. Sato;Shiro Yoshimatsu
本报告涉及流行性脑炎的血象特征，我们相信，这将证明对诊断和预后极有价值。有限的可用临床材料和能力，以解释我们的工作的一些特点，阻止了事实的早期介绍。然而，我们中的一位最近进行的一系列动物实验的结果证实了两年前收集的临床证据。简而言之，这一证据可以概括为：Sato和Sekiya对髓系白细胞的过氧化物酶试验（铜法）在典型流行性脑炎的急性病例（伴嗜睡、眼肌麻痹和虚弱或发热）中为阴性，但在任何其他疾病中为阳性，无论是感染性还是非感染性起源。只有用铜法进行过氧化物酶试验时才是如此，我们认为铜法在简便、灵敏、稳定性方面上级其他过氧化物酶法
This report concerns a characteristic feature of the blood picture of epidemic encephalitis which, we believe, will prove extremely valuable in diagnosis and prognosis. Limitation of available clinical material and in ability to explain some features of our work have prevented an earlier presentation of the facts. However, the results of a series of animal experiments carried out by one of us 1 recently have substantiated the clinical evidence assembled two years ago. Briefly, this evidence can be summarized: The peroxidase test (copper method) of Sato and Sekiya on myeloid leukocytes is negative in an acute case of typical epidemic encephalitis (with lethargy, ophthalmoplegia, and asthenia or fever), but is positive in any other disease, whether of infectious or non-infectious origin. This is true only of the peroxidase test as done by the copper method, which we believe is superior to other peroxidase methods in simplicity, in sensitivity, in constancy