FrontiERs: movers and shapers of the higher plant cortical endoplasmic reticulum.
FrontiERs: movers and shapers of the higher plant cortical endoplasmic reticulum.
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DOI：
10.1016/j.pbi.2011.07.006
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发表时间：
2011-12
影响因子：
9.5
通讯作者：
I. Sparkes;C. Hawes;L. Frigerio
中科院分区：
文献类型：
--
作者：
I. Sparkes;C. Hawes;L. Frigerio
高等植物的内质网（ER）具有许多重要的功能，但我们对其复杂的网络形状和动力学与功能的关系的理解非常有限。最近的工作已经开始解开关键的分子球员在产生的多形性，高度动态的ER网络结构，遍布整个细胞质。内质网运动依赖于肌动蛋白。ER的形状取决于RHD3（根毛缺陷3）和一个称为网状蛋白的蛋白质家族。摆在面前的主要挑战是了解控制ER形状和运动的因素是如何调节的，以及这与ER的众多功能之间的关系。
The endoplasmic reticulum (ER) in higher plants performs many important functions, yet our understanding of how its intricate network shape and dynamics relate to function is very limited. Recent work has begun to unpick key molecular players in the generation of the pleomorphic, highly dynamic ER network structure that pervades the entire cytoplasm. ER movement is acto-myosin dependent. ER shape is dependent on RHD3 (Root Hair Defective 3) and a family of proteins called reticulons. The major challenge that lies ahead is understanding how factors that control ER shape and movement are regulated and how this relates to the numerous functions of the ER.