The pangenome of an agronomically important crop plant Brassica oleracea.
The pangenome of an agronomically important crop plant Brassica oleracea.
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DOI：
10.1038/ncomms13390
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发表时间：
2016-11-11
影响因子：
16.6
通讯作者：
Edwards, David
中科院分区：
文献类型：
--
作者：
Golicz, Agnieszka A.;Bayer, Philipp E.;Barker, Guy C.;Edger, Patrick P.;Kim, HyeRan;Martinez, Paula A.;Chan, Chon Kit Kenneth;Severn-Ellis, Anita;McCombie, W. Richard;Parkin, Isobel A. P.;Paterson, Andrew H.;Pires, J. Chris;Sharpe, Andrew G.;Tang, Haibao;Teakle, Graham R.;Town, Christopher D.;Batley, Jacqueline;Edwards, David
越来越多的人意识到，由于结构变异，代表单个个体基因组的参考序列无法捕获该物种中发现的所有基因库。大量的基因受存在/不存在和拷贝数变异的影响，这表明它可能有助于表型和农艺性状的多样性。在这里，我们通过对甘蓝全基因组的分析表明，近20%的基因受到存在/不存在变异的影响。显示存在/不存在变异的几个基因被注释与主要农艺性状相关的功能，包括抗病性、开花时间、硫苷代谢和维生素生物合成。 甘蓝是一个单一物种，包括卷心菜、西兰花和布鲁塞尔豆芽等多种作物。在这里，作者确定了现有B中未捕获的基因。通过泛基因组的组装，显示出可能与重要农艺性状相关的基因内容的变化
There is an increasing awareness that as a result of structural variation, a reference sequence representing a genome of a single individual is unable to capture all of the gene repertoire found in the species. A large number of genes affected by presence/absence and copy number variation suggest that it may contribute to phenotypic and agronomic trait diversity. Here we show by analysis of the Brassica oleracea pangenome that nearly 20% of genes are affected by presence/absence variation. Several genes displaying presence/absence variation are annotated with functions related to major agronomic traits, including disease resistance, flowering time, glucosinolate metabolism and vitamin biosynthesis. Brassica oleracea is a single species that includes diverse crops such as cabbage, broccoli and Brussels sprouts. Here, the authors identify genes not captured in existing B. oleracea reference genomes by the assembly of a pangenome and show variations in gene content that may be related to important agronomic traits
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影响因子：
48
作者：
Langmead, Ben;Salzberg, Steven L.
通讯作者：
Salzberg, Steven L.
影响因子：
4.4
作者：
Lin K;Zhang N;Severing EI;Nijveen H;Cheng F;Visser RG;Wang X;de Ridder D;Bonnema G
通讯作者：
Bonnema G
影响因子：
64.8
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Mott R
大豆野生近缘种的从头组装，用于多样性和农艺性状的全基因组分析
影响因子：
46.9
作者：
Li, Ying-hui;Zhou, Guangyu;Qiu, Li-juan
通讯作者：
Qiu, Li-juan
影响因子：
11.6
作者：
Kliebenstein, DJ;Lambrix, VM;Mitchell-Olds, T
通讯作者：
Mitchell-Olds, T