Complexes of Calcium with Citric Acid and Tricarballylic Acids measured by Ion Exchange
Complexes of Calcium with Citric Acid and Tricarballylic Acids measured by Ion Exchange
复制标题
通过离子交换测量钙与柠檬酸和三羧酸的络合物
DOI：
10.1038/166913b0
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发表时间：
1950
期刊：
影响因子：
64.8
通讯作者：
A. Lindenbaum
中科院分区：
文献类型：
--
作者：
J. Schubert;A. Lindenbaum
我们致力于研究金属离子和阴离子相互作用产生的络合离子的组成和稳定性，特别是那些具有生物重要性的离子。通过测量合成有机阳离子交换剂在已知浓度的复合离子形成阴离子1-3存在下吸收放射性阳离子的示踪剂水平(∼10−8M)进行测定。这种离子交换程序有几个独特的优点1。例如，可以在同一溶液中同时测量几种不同的金属-有机酸络离子的离解常数，不需要对形成络合离子的阴离子的量进行校正，并且可以在相同的体系中研究离子强度、温度或介电常数等因素在溶液中的梯度变化的影响。阳离子交换树脂，如‘Dowex 50’4(由密歇根州米德兰的陶氏化学公司制造)。现在用于我们的实验，因为它们的容量与pH无关。
WE are engaged in a study of the composition and stability of the complex ions which result from the interaction between metal ions and anions, particularly those of biological importance. The determinations are made by measuring the degree to which tracer levels (∼ 10−8M) of a radioactive cation are taken up by a synthetic organic cation exchanger in the presence of known concentrations of a complex ion-forming anion1–3. This ion-exchange procedure has several unique advantages1. For example, the dissociation constants of several different metal–organic acid complex ions can be measured simultaneously in the same solution, no corrections are needed for the amount of anion utilized for the formation of the complex ion, and the effect of graded changes in the solutions of such factors as ionic strength, temperature, or dielectric constant can be studied on the same systems. Cation exchange resins such as ‘Dowex 50’4(manufactured by the Dow Chemical Co., Midland, Mich.) are now used in our experiments because their capacity is independent of thepH.