Exploring zebrafish genomic, functional and phenotypic data using ZFIN.
Exploring zebrafish genomic, functional and phenotypic data using ZFIN.
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DOI：
10.1002/0471250953.bi0118s31
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发表时间：
2010-09-01
影响因子：
--
通讯作者：
Sprague, Judy
中科院分区：
文献类型：
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作者：
Ramachandran, Sridhar;Ruef, Barbara;Sprague, Judy
斑马鱼模式生物数据库（ZFIN）提供了斑马鱼基因组、遗传、发育和表型数据的网络资源。ZFIN整理和整合来自当前文献和实验室直接提交的数据。此外，ZFIN还与其他生物信息学组织合作，提供其他相关数据的链接。这些数据可以通过各种基于网络的搜索和显示工具访问。本单元重点介绍搜索、可视化和分析ZFIN数据的一些基本方法，包括基因、基因表达、突变体、变形体、转基因、解剖结构和抗体。还讨论了ZFIN的GBrowse基因组查看器、BLAST以及协议和抗体wiki。
The zebrafish model organism database (ZFIN) provides a Web resource of zebrafish genomic, genetic, developmental, and phenotypic data. ZFIN curates and integrates data from current literature and from direct data submissions from laboratories. In addition, ZFIN collaborates with other bioinformatics organizations to provide links to other relevant data. These data can be accessed through a variety of Web-based search and display tools. This unit focuses on some of the basic methods to search, visualize, and analyze ZFIN data, including genes, gene expression, mutants, morphants, transgenics, anatomical structures, and antibodies. ZFIN's GBrowse genome viewer, BLAST, and protocol and antibody wikis are also discussed.