A SIMPLE EQUATION FOR THE DESCRIPTION OF SOLUTE RELEASE .3. COUPLING OF DIFFUSION AND RELAXATION

A SIMPLE EQUATION FOR THE DESCRIPTION OF SOLUTE RELEASE .3. COUPLING OF DIFFUSION AND RELAXATION
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DOI:
10.1016/0378-5173(89)90306-2
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发表时间:
1989-12-01
影响因子:
5.8
通讯作者:
SAHLIN, JJ
SAHLIN, JJ
中科院分区:
医学2区
文献类型:
--
作者:
PEPPAS, NA;SAHLIN, JJ

文献摘要

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聚合物装置中溶质释放的指数表达式可以用释放机制的S扩散和松弛贡献来表示。这个方程的一般形式S指数通过释放装置的长径比与释放装置的几何形状有关。本文提出了一种利用扩散/松弛耦合模型来分析控制释放系统的释放行为的方法。
The exponential expression of solute release from polymeric devices can be written in terms of the release mechanism''s diffusional and relaxational contributions. The general form of this equation''s exponent is related to the geometric shape of the releasing device through its aspect ratio. A methodology is presented for general analysis of the release behavior of controlled release systems using a coupled diffusion/relaxation model.