Asymptomatic Cases and Limited Transmission of SARS-CoV-2 in Residents and Healthcare Workers in Three Dutch Nursing Homes.
Asymptomatic Cases and Limited Transmission of SARS-CoV-2 in Residents and Healthcare Workers in Three Dutch Nursing Homes.
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DOI：
10.1177/2333721420982800
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发表时间：
2020-01
影响因子：
2.7
通讯作者：
COVID-19 NH-Study Group
中科院分区：
文献类型：
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作者：
van Buul LW;van den Besselaar JH;Koene FMHPH;Buurman BM;Hertogh CMPM;COVID-19 NH-Study Group**;COVID-19 NH-Study Group
我们的目的是评估的贡献，和前驱居民和医护人员在传播SARS-CoV-2在养老院。我们进行了两个连续的点患病率调查，包括标准化症状评估和鼻咽和口咽测试的SARS-CoV-2，297名居民和542名医护人员的三个荷兰疗养院（NH）与最近的SARS-CoV-2介绍。在第一次流行病学调查中，15名居民检测呈阳性，其中1名为症状前患者，3名仍无症状。在第二次流行病学调查中，一名居民和一名医护人员检测出SARS-CoV-2阳性，两人均无症状。虽然确定了有限数量的SARS-CoV-2阳性病例，但这项研究证实了COVID-19的症状发生。我们还描述了可能有助于预防传播的因素。综上所述，我们的研究补充了对NHS中有效SARS-CoV-2筛查的讨论。
We aimed to assess the contribution of a- and presymptomatic residents and healthcare workers in transmission of SARS-CoV-2 in nursing homes. We conducted two serial point-prevalence surveys, including standardized symptom assessment and nasopharyngeal and oropharyngeal testing for SARS-CoV-2, among 297 residents and 542 healthcare workers of three Dutch nursing homes (NHs) with recent SARS-CoV-2 introduction. At the first point-prevalence survey, 15 residents tested positive of which one was presymptomatic and three remained asymptomatic. At the second point-prevalence survey one resident and one healthcare worker tested SARS-CoV-2 positive and both remained asymptomatic. Although a limited number of SARS-CoV-2 positive cases were identified, this study confirms a- and presymptomatic occurrence of Covid-19. We additionally describe factors that may contribute to the prevention of transmission. Taken together, our study complements the discussion on effective SARS-CoV-2 screening in NHs.