Compliance Issues in Outpatient Treatment
Compliance Issues in Outpatient Treatment
复制标题
门诊治疗的合规性问题
DOI：
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发表时间：
1985
影响因子：
2.9
通讯作者：
J. Kane
中科院分区：
文献类型：
--
作者：
J. Kane
在精神科门诊病人中，估计40%至50%的依从率是常见的。在疾病的急性期，可能的不依从者包括躁狂患者、偏执型精神分裂症患者和深度抑郁症患者。长期预防性或维持治疗期的不依从性往往会随着时间的推移而增加。不遵守的原因是多方面的。使用长效肠外精神抑制剂可能有助于降低不依从性的发生率，尽管难以获得相关文件。由于迟发性运动障碍的风险，应使用尽可能低剂量的长效药物。目前正在进行研究，以确定防止复发和尽量减少不良影响所需的最低有效剂量。
Estimated compliance rates of 40 to 50% are common among psychiatric outpatients. Likely noncompliers in the acute phase of illness include manic patients, paranoid schizophrenics, and the profoundly depressed. Noncompliance during the long-term prophylactic or maintenance treatment phase tends to increase with the passage of time. The cause of noncompliance is multifactorial. The use of long acting parenteral neuroleptic agents may help decrease the incidence of noncompliance, although documentation is difficult to obtain. Because of the risk of tardive dyskinesia, the lowest possible dose of the depot medication should be used. Studies are now under way to ascertain minimal effective doses necessary to prevent relapse and minimize adverse effects.