Cortical Spreading Depolarizations and Clinically Measured Scalp EEG Activity After Aneurysmal Subarachnoid Hemorrhage and Traumatic Brain Injury.
Cortical Spreading Depolarizations and Clinically Measured Scalp EEG Activity After Aneurysmal Subarachnoid Hemorrhage and Traumatic Brain Injury.
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DOI：
10.1007/s12028-021-01418-7
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发表时间：
2022-06
影响因子：
3.5
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中科院分区：
文献类型：
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扩张性去极化（SDs）与蛛网膜下腔出血（SAH）和创伤性脑损伤（TBI）后的预后较差有关，但金标准检测需要硬膜下带状电极皮质电成像。脑电图（EEG）初-间期连续异常与TBI后的不良预后、延迟性脑缺血（DCI）和SAH后的不良预后相关。我们用脑实质内和硬脑膜下条状电极检查了SAH和TBI患者的SD检出率，并评估了连续脑电图（cEEG）测量与颅内量化SD的相关性。在这个单中心队列中，我们纳入了SAH和TBI患者，他们接受了≥24小时可解释的颅内监测，通过8点接触脑内或6点接触硬膜下条状铂电极或两者同时进行。根据建立的共识标准对SDs进行评分，并将其与根据美国临床神经生理学会危重监护EEG监测共识标准（侧化节律性δ活动、全面性节律性δ活动、侧化周期性放电、全面性周期性放电、任何发作-间期连续体或用于癫痫发作风险评估的复合头皮EEG工具：2HELPS2B评分）评定的脑电图结果进行比较。在SAH患者中，cEEG被评估为有效的DCI生物标志物：新的或恶化的癫痫样异常和新的背景恶化。6年多来，28例脑实质内电极记录的患者中有5例（18%）出现SDs， 10例硬膜下条状电极记录的患者中有4例（40%）出现SDs。SDs的发生与第1天的脑电图结果之间没有显著关联（美国临床神经生理学学会主要术语：侧化周期性放电、广泛性周期性放电、侧化节律性三角洲活动或癫痫发作，单独或联合）。SAH后，已建立的cEEG DCI预测因子与SDs无关。脑实质内记录的SD率较低，且记录的SD与发作间期连续异常或其他cEEG DCI预测因子无关。识别头皮脑电图相关的SD可能需要训练计算脑电图分析和使用金标准硬膜下条状皮质电成像记录。
Spreading depolarizations (SDs) are associated with worse outcome following subarachnoid hemorrhage (SAH) and traumatic brain injury (TBI), but gold standard detection requires electrocorticography with a subdural strip electrode. Electroencephalography (EEG) ictal–interictal continuum abnormalities are associated with poor outcomes after TBI and with both delayed cerebral ischemia (DCI) and poor outcomes after SAH. We examined rates of SD detection in patients with SAH and TBI with intraparenchymal and subdural strip electrodes and assessed which continuous EEG (cEEG) measures were associated with intracranially quantified SDs. In this single-center cohort, we included patients with SAH and TBI undergoing ≥24 h of interpretable intracranial monitoring via eight-contact intraparenchymal or six-contact subdural strip platinum electrodes or both. SDs were rated according to established consensus criteria and compared with cEEG findings rated according to the American Clinical Neurophysiology Society critical care EEG monitoring consensus criteria: lateralized rhythmic delta activity, generalized rhythmic delta activity, lateralized periodic discharges, generalized periodic discharges, any ictal–interictal continuum, or a composite scalp EEG tool for seizure risk estimation: the 2HELPS2B score. Among patients with SAH, cEEG was assessed for validated DCI biomarkers: new or worsening epileptiform abnormalities and new background deterioration. Over 6 years, SDs were recorded in 5 (18%) of 28 patients recorded with intraparenchymal electrodes and 4 (40%) of 10 patients recorded with subdural strip electrodes. There was no significant association between occurrence of SDs and day 1 cEEG findings (American Clinical Neurophysiology Society main terms lateralized periodic discharges, generalized periodic discharges, lateralized rhythmic delta activity, or seizures, individually or in combination). After SAH, established cEEG DCI predictors were not associated with SDs. Intraparenchymal recordings yielded low rates of SD, and documented SDs were not associated with ictal–interictal continuum abnormalities or other cEEG DCI predictors. Identifying scalp EEG correlates of SD may require training computational EEG analytics and use of gold standard subdural strip electrocorticography recordings.
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影响因子：
11.2
作者：
Rosenthal ES;Biswal S;Zafar SF;O'Connor KL;Bechek S;Shenoy AV;Boyle EJ;Shafi MM;Gilmore EJ;Foreman BP;Gaspard N;Leslie-Mazwi TM;Rosand J;Hoch DB;Ayata C;Cash SS;Cole AJ;Patel AB;Westover MB
通讯作者：
Westover MB
影响因子：
11.2
作者：
Bosche, Bert;Graf, Rudolf;Ernestus, Ralf-Ingo;Dohmen, Christian;Reithmeier, Thomas;Brinker, Gerrit;Strong, Anthony J.;Dreier, Jens P.;Woitzik, Johannes
通讯作者：
Woitzik, Johannes
影响因子：
14.5
作者：
Dreier, Jens P.;Woitzik, Johannes;Strong, Anthony J.
通讯作者：
Strong, Anthony J.
影响因子：
11
作者：
Roos, YBWEM;de Haan, RJ;Vermeulen, M
通讯作者：
Vermeulen, M
DOI：
10.1097/wnp.0000000000000281
发表时间：
2016-06
期刊：
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
影响因子：
--
作者：
Muniz CF;Shenoy AV;OʼConnor KL;Bechek SC;Boyle EJ;Guanci MM;Tehan TM;Zafar SF;Cole AJ;Patel AB;Westover MB;Rosenthal ES
通讯作者：
Rosenthal ES