Host condition and individual risk of cowpox virus infection in natural animal populations: cause or effect?
Host condition and individual risk of cowpox virus infection in natural animal populations: cause or effect?
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DOI：
10.1017/s0950268808001866
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发表时间：
2009-09-01
影响因子：
4.2
通讯作者：
Begon, M.
中科院分区：
文献类型：
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作者：
Beldomenico, P. M.;Telfer, S.;Begon, M.
最近的研究提供了证据，地方病病原体可能会影响动物的动态。然而，这些研究通常没有考虑到受感染的个体可能有一个先前的潜在的不良状况。我们研究了是否个人在恶劣的条件下更有可能成为感染的地方性病原体，作为一个系统的牛痘病毒在田鼠的动态。根据每月抽样的田鼠种群数据，巢式病例对照研究评估了条件较差的易感个体是否具有较高的感染牛痘的概率。条件的影响被认为是相当大的，特别是对男性。有时，身体状况良好的易感男性被感染的可能性相对较低，一个身体状况差的易感男性感染牛痘的可能性是常人的两倍; 2如果这名男性还患有贫血症，那么感染牛痘的可能性几乎是常人的四倍。我们讨论了在解释野生动物疾病研究结果时需要注意的问题。
Recent studies have provided evidence that endemic pathogens may affect dynamics in animals. However, such studies have not typically considered that infected individuals might have a preceding underlying poor condition. We examined whether individuals in poor condition are more likely to become infected by an endemic pathogen, using as a system the dynamics of cowpox virus in field voles. With data from monthly sampled vole populations, a nested case-control study evaluated whether Susceptible individuals with poorer condition had higher probabilities of contracting cowpox. The influence of condition was found to be considerable, especially for males. At times when a susceptible male with good body condition had a relatively low probability of becoming infected., a susceptible male with poor body condition was twice as likely to contract cowpox; if this male was also anaemic, the chances were almost quadrupled. We discuss the care needed when interpreting the findings of wildlife disease studies.